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IJERPH
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Advances in Male Reproductive Health and Urology
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Advances in Male Reproductive Health and Urology

A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601).

Deadline for manuscript submissions: 31 July 2024 | Viewed by 8389

Special Issue Editor

Dr. Guglielmo Mantica

E-Mail Website
Guest Editor
Department of Urology, Policlinico San Martino Hospital, University of Genova, 16132 Genova, Italy
Interests: endourology; andrology; laparoscopy; kidney cancer; bladder cancer; prostate cancer; urethroplasty; kidney stones; social media; urogenital infections

Special Issue Information

Dear Colleagues,

We are currently organizing a Special Issue to be published in the International Journal of Environmental Research and Public Health. This Special Issue will focus on male reproductive health and urology.

The International Journal of Environmental Research and Public Health is a peer-reviewed scientific journal that publishes articles and communications pertaining to the interdisciplinary research area of environmental health sciences and public health. For more detailed information on the journal, please visit the following website: https://www.mdpi.com/journal/ijerph. 

Male reproductive health is a branch deeply connected with public health, associated with various problems, both in developing and western countries. Similarly, urology is a branch that treats widely diffused pathologies, both in the young/pediatric population and in the elderly population, such as urolithiasis, BPH, and genitourinary cancers. These diseases lead to countless treatments and hospitalizations, which, especially in public health emergencies, such as that experienced over the last two years, represent a huge problem that may no longer be sustainable by most healthcare systems in the future.

In this regard, this Special Issue is open to any subject area related to the impacts of the built environment on public health. This includes technological and pharmacological advances, both in the andrological and urological fields, that can bring benefits, in terms of reduced hospitalization, but also a simple improvement in the quality of care and patients’ outcomes.

The keywords suggest just a few of the many possibilities of topics accepted for publication in this Special Issue.

Please note that clinical studies not sufficiently addressing the aim of the journal will not be considered.

Dr. Guglielmo Mantica
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Environmental Research and Public Health is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2500 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • andrology
  • aging male
  • public health
  • genitourinary cancer
  • laparoscopy
  • robotic surgery
  • quality of life
  • urolithiasis
  • BPH
  • pediatric urology
  • reproductive medicine
  • new technologies
  • biomarkers
  • reconstructive urology
  • urethroplasty

Published Papers (3 papers)

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Research

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13 pages, 1131 KiB  
Article
Maternal Serum α-Fetoprotein Levels during Pregnancy and Testicular Cancer in Male Offspring: A Cohort Study within a Danish Pregnancy Screening Registry
by Cecilie S. Uldbjerg, Youn-Hee Lim, Clara H. Glazer, Russ Hauser, Anders Juul and Elvira V. Bräuner
Int. J. Environ. Res. Public Health 2022, 19(21), 14112; https://doi.org/10.3390/ijerph192114112 - 28 Oct 2022
Cited by 2 | Viewed by 2937
Abstract
Testicular cancer is believed to originate from disruptions of normal androgen-estrogen balance in-utero. α-fetoprotein (AFP) may modify fetal response to estrogens via estrogen interaction. In a cohort study, we investigated the association between circulating maternal pregnancy AFP and testicular cancer risk in offspring. [...] Read more.
Testicular cancer is believed to originate from disruptions of normal androgen-estrogen balance in-utero. α-fetoprotein (AFP) may modify fetal response to estrogens via estrogen interaction. In a cohort study, we investigated the association between circulating maternal pregnancy AFP and testicular cancer risk in offspring. Of the 56,709 live-born males from a pregnancy screening registry in 1980–1995, our study included 50,519 singleton males with available second trimester blood samples from their mothers and complete covariate ascertainment. Testicular cancer diagnoses and covariate data were obtained from nationwide Danish health registries. Cox regression and Kaplan–Meier analyses estimated the prospective risk of testicular cancer (all, seminoma, nonseminoma) by AFP multiples of the median. During follow-up, 163 (0.3%) of the included males developed testicular cancer, of which 89 (54.6%) were nonseminomas. Maternal serum AFP levels greater than/equal to the median were associated with a relative risk of testicular cancer close to unity (RR 1.04, 95% CI 0.76; 1.41) compared to AFP below the median. Associations differed by type of testicular cancer (RRseminoma 0.81, 95% CI 0.51; 1.29, RRnonseminoma 1.31, 95% CI 0.85; 2.02). On balance, our findings do not support that serum AFP in pregnancy can be used as a predictor of testicular cancer in offspring. Full article
(This article belongs to the Special Issue Advances in Male Reproductive Health and Urology)
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9 pages, 616 KiB  
Article
Verbal Instruction for Pelvic Floor Muscle Contraction among Healthy Young Males
by Noa Ben Ami, Ron Feldman and Gali Dar
Int. J. Environ. Res. Public Health 2022, 19(19), 12031; https://doi.org/10.3390/ijerph191912031 - 23 Sep 2022
Cited by 1 | Viewed by 2001
Abstract
Teaching Pelvic Floor Muscle (PFM) contraction is a challenging task for clinicians and patients, as these muscles cannot be directly visualized. Thus, this study’s objective is to compare the effectiveness of six verbal instructions for contracting the PFM among young men, as observed [...] Read more.
Teaching Pelvic Floor Muscle (PFM) contraction is a challenging task for clinicians and patients, as these muscles cannot be directly visualized. Thus, this study’s objective is to compare the effectiveness of six verbal instructions for contracting the PFM among young men, as observed with transabdominal ultrasound imaging. Thirty-five male physiotherapy students, mean age 25.9 ± 1.9 years, participated in the study. A 6 MHz 35-mm curved linear array ultrasound transducer (Mindray M5) was placed in the transverse plane, supra-pubically, and angled 15–30° from the vertical plane. During crook lying, participants received six verbal instructions for contracting the PFM, with bladder base displacement and endurance evaluated. Following the instructions, “squeeze your anus”, “shorten the penis”, and “elevate the scrotum”, over 91% of the participants performed a cranial (upward) bladder base displacement. During instruction six, “draw in”, which involves breathing, the PFM, and the transversus abdominis, only 25% performed cranial bladder base displacement (p < 0.001), and the endurance was the lowest (p < 0.001). Our findings suggest that several simple verbal instructions can be used for teaching PFM contraction to young males. Moreover, two instructions should be avoided: “draw in” and the general instruction “squeeze your PFM”, as they did not produce effective elevation of the bladder base. Full article
(This article belongs to the Special Issue Advances in Male Reproductive Health and Urology)
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Review

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20 pages, 756 KiB  
Review
The Role of Novel Bladder Cancer Diagnostic and Surveillance Biomarkers—What Should a Urologist Really Know?
by Rafaela Malinaric, Guglielmo Mantica, Lorenzo Lo Monaco, Federico Mariano, Rosario Leonardi, Alchiede Simonato, André Van der Merwe and Carlo Terrone
Int. J. Environ. Res. Public Health 2022, 19(15), 9648; https://doi.org/10.3390/ijerph19159648 - 5 Aug 2022
Cited by 10 | Viewed by 2674
Abstract
The aim of this review is to analyze and describe the current landscape of bladder cancer diagnostic and surveillance biomarkers. We researched the literature from 2016 to November 2021 to find the most promising new molecules and divided them into seven different subgroups [...] Read more.
The aim of this review is to analyze and describe the current landscape of bladder cancer diagnostic and surveillance biomarkers. We researched the literature from 2016 to November 2021 to find the most promising new molecules and divided them into seven different subgroups based on their function and location in the cell. Although cystoscopy and cytology are still the gold standard for diagnosis and surveillance when it comes to bladder cancer (BCa), their cost is quite a burden for national health systems worldwide. Currently, the research is focused on finding a biomarker that has high negative predictive value (NPV) and can exclude with a certainty the presence of the tumor, considering missing it could be disastrous for the patient. Every subgroup has its own advantages and disadvantages; for example, protein biomarkers cost less than genomic ones, but on the other hand, they seem to be less precise. We tried to simplify this complicated topic as much as possible in order to make it comprehensible to doctors and urologists that are not as familiar with it, as well as encourage them to actively participate in ongoing research. Full article
(This article belongs to the Special Issue Advances in Male Reproductive Health and Urology)
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