Surgical Treatment in Medication-Related Osteonecrosis of the Jaw in Elderly People
A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601). This special issue belongs to the section "Oral Health".
Deadline for manuscript submissions: closed (30 April 2021) | Viewed by 2436
Special Issue Editors
Interests: nerve regeneration; bone regeneration; oral cancer; jaw deformity; cleft lip; oral disease
Special Issue Information
Dear Colleagues,
We are organizing a Special Issue on the impact of surgical treatment in medication-related osteonecrosis of the jaw in elderly people in the International Journal of Environmental Research and Public Health. The venue is a peer-reviewed scientific journal that publishes articles and communications in the interdisciplinary area of environmental health sciences and public health. For detailed information on the journal, we refer you to https://www.mdpi.com/journal/ijerph.
Bisphosphonate (BP)-induced avascular necrosis of the jaw was first reported by Marx in 2003, but among the various bisphosphonates used to treat osteoporosis, only those containing nitrogen cause avascular necrosis. This disease has been named bisphosphonate-related osteonecrosis of jaw (BRONJ), and many studies have been undertaken to determine its cause, but no definite pathogenesis has been elucidated so far. Research on MRONJ is being actively conducted worldwide. In 2014, the American Association of Oral and Maxillofacial Surgeons (AAOMS) reported that antiangiogenic and antiresorptive agents also cause avascular necrosis of the jaw and proposed that the disease be called medication-related osteonecrosis (MRONJ). These drugs cause MRONJ in the oral cavity, but those offer many clinical benefits, including a reduced incidence of skeletal-related events (e.g., pathological fractures and spinal cord compression) and a reduced need for radiation or surgery on bone. However, MRONJ can be challenging to treat and can cause significant pain and reduced quality of life. Because of it, medical experts in various fields are creating guidelines to prevent and treat it to improve the quality of life of patients. Additionally, there are many studies to reduce prevalence of MRONJ by preventive oral care methods combined with effective oral health practices.
With this Special Issue, we invite you to submit high-quality original research articles or reviews that provide solid new findings extending the current state of knowledge. All manuscripts will be peer-reviewed by experts in the field and would be due no later than the end of April 2021.
Dr. Dae-Seok Hwang
Prof. Dr. Uk-kyu Kim
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Environmental Research and Public Health is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2500 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- MRONJ
- BRONJ
- bisphosphonate
- osteoporosis
