Drug Discovery: Using Zebrafish and Medaka
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pharmacology".
Deadline for manuscript submissions: closed (31 May 2023) | Viewed by 2299
Special Issue Editors
Interests: zebrafish; drug discovery; brain disease; neurodegenerative diseases; stroke; Alzheimer’s disease
Interests: medaka; genetic engineering; live imaging; drug discovery; disease model; nervous system; lymphatic vasculature
Special Issue Information
Dear Colleagues,
Although zebrafish and medaka are vertebrates, their embryos are transparent, their breeding is easy, their life cycle is short, and it is easy to create mutations and genetically modified animals. These approaches are used in research on biological control such as development and regeneration. In recent years, the spirit of animal welfare has increased demand as an alternative to mammalian models.
Recently, disease model research using zebrafish and medaka, basic research with a view to drug discovery, pharmacological action, and compound screening research are increasing and attracting more and more attention. Expectations are also growing around fish models as an evaluation system for animal experiments to replace mammals, not only in the development of pharmaceuticals, but also in the development of cosmetics, foods and supplements, and in environmental surveys.
In this Special Issue, we invite the submission of research on disease models and toxicity tests aimed at drug discovery using fish such as zebrafish and medaka.
Dr. Toshiaki Kume
Dr. Tomonori Deguchi
Guest Editors
Manuscript Submission Information
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Keywords
- zebrafish
- medaka
- drug discovery
- live imaging
- drug screening
- disease model
