Recent Progress in Antipsychotic Treatment
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 30 January 2025 | Viewed by 53
Special Issue Editor
Special Issue Information
Dear Colleagues,
This Special Issue will summarize the mechanisms of molecular action in antipsychotic treatment, presenting preclinical and clinical studies. Since the 1950s, the use of antipsychotic treatment has expanded beyond schizophrenia to include other psychotic disorders. Antipsychotics alleviate agitation in dementia, Alzheimer disease, and autism and are effective in tics and Tourette syndrome. Their complex mechanisms present challenges due to their different affinities for dopamine, serotonergic, adrenergic, histaminergic, and muscarinic receptors. We invite the submission of reviews, systematic reviews, meta-analyses, and/or research articles on the following topics related to the molecular mechanisms behind antipsychotics:
- Neurobiology of schizophrenia and other psychotic disorders;
- Neuropharmacology, effects, and side effects of antipsychotics;
- Effects on brain activity and metabolism;
- Effects on reward signaling and cognitive functions;
- Effects of dopamine receptors and their modulation on prefrontal and striatal neuron activity;
- Effects on hunger- and palatability-driven feeding;
- Effects on agitation, aggression, or anxiety;
- Current clinical trials: new indications and new molecular targets and their mechanisms.
Dr. Rita Gálosi
Guest Editor
Manuscript Submission Information
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Keywords
- antipsychotics
- receptorial mechanisms
- modulation of dopamine receptors
- antagonist
- partial agonist
- psychotic disorders
- prefrontal cortex
- limbic system
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