Recent Advances in Drug Discovery
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (20 October 2023) | Viewed by 15300
Special Issue Editors
Interests: pharmacology of pain; inflammation; cancer; natural products
Special Issues, Collections and Topics in MDPI journals
2. Programa de Pós-Graduação em Farmacologia e Química Medicinal, Instituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-909, Brazil
Interests: medicinal chemistry; drug design and discovery; multitarget drugs for neurodegenerative diseases; use of privileged structures to design new epigenetic drug candidates; discovery of new kinase inhibitors for chronic inflammatory diseases
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The discovery of new drugs is a continuous objective of researchers in academia and pharmaceutical companies. The processes of drug discovery provide an important source of new drug prototypes for future drug development, which may result in new medicines. While numerous developments have be seen, including a reduction in the timescales, complexity, and cost and enhancement of the the precision, there is still a long way to go. These facts still represent challenges to modern drug discovery. The discovery of new drugs is hard because it is very rare to discover a molecule—either natural or artificial—that is a hit against a protein target implicated in a disease. This difficult may occur due to a variety of reasons, including toxicity, efficacy, physicochemical properties, bioavailability, or inadequate drug performance. In view of these, the continuous search for new compounds with high potency and lesser side effects is a permanent objective.
This Special Issue, “Recent Advances in Drug Discovery”, will focus on synthesis and/or biological effects of new compounds designed using medicinal chemistry approaches looking for improving activities against worldwide diseases, including, but not limited to, neglect diseases, chronic inflammatory diseases, cancer, tropical diseases (malaria, leishmaniosis, dengue, zika), and neurological diseases.
We look forward to your contribution to this exciting Special Issue.
Dr. Patricia Dias Fernandes
Prof. Dr. Carlos Alberto Manssour Fraga
Guest Editors
Manuscript Submission Information
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Keywords
- medicinal chemistry
- inflammation
- cancer
- pain
- drug design and discovery
- chronic inflammatory diseases
- neglected diseases
- drug screening
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