New Insight into Extracellular Vesicles in Proliferative Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".
Deadline for manuscript submissions: 20 December 2024 | Viewed by 2872
Special Issue Editor
2. Universidad Complutense de Madrid, 28040 Madrid, Spain
Interests: extracellular vesicles; intercellular communication; pulmonary hypertension; ARDS; metastasis; mitochondrial function
Special Issue Information
Dear Colleagues,
The excessive proliferation of cells and turnover of the cellular matrix contribute significantly to the pathogenesis of several diseases, including cancer, atherosclerosis, rheumatoid arthritis, psoriasis, idiopathic pulmonary fibrosis, pulmonary hypertension, scleroderma and cirrhosis of the liver. The mechanisms that control the spread of damage in these types of pathologies are not entirely clear. In recent years, interest in the different types of extracellular vesicles (exosomes, microvesicles, apoptotic bodies or newly identified subpopulations such as oncosomes, migrasomes, exophers, etc.) and their roles as mediators of intercellular and interorgan communication has increased exponentially. Extracellular vesicles (EVs) are nanosized lipid membrane-enclosed vesicles that may contain nucleic acids (DNAs, mRNAs, miRNAs, lncRNAs, piRNAs, etc.), lipids, proteins and organelles and may participate in the dissemination of the proliferative phenotype or in the possible therapeutic effects of these types of pathologies.
In this Special Issue, we aim to highlight the role of extracellular vesicles in proliferative diseases. Therefore, we invite researchers to contribute original research and up-to-date review articles that increase knowledge about the mechanisms involved in the synthesis, cargo or internalization of these vesicles. We also welcome articles that explore their use as biomarkers.
Dr. Sergio Esquivel-Ruiz
Guest Editor
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Keywords
- proliferation
- extracellular vesicles
- intercellular communication
- vesicle cargo
- therapeutic applications
- biomarkers
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