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Metal Nanoparticles: From Fundamental Studies to New Applications

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Materials Science".

Deadline for manuscript submissions: 31 August 2024 | Viewed by 985

Special Issue Editors


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Guest Editor
Institute of Chemistry and Technical Electrochemistry, Faculty of Chemical Technology, Poznan University of Technology, Berdychowo 4, 60-965 Poznan, Poland
Interests: metal and non-metal nanostructures; nanostructures stabilized by biopolymers; properties and application of nanostructures; polymer fillers
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Guest Editor
Institute of Chemistry and Technical Electrochemistry, Faculty of Chemical Technology, Poznan University of Technology, Berdychowo 4, 60-965 Poznan, Poland
Interests: modified electrodes; doped electrodes; metal nanoparticles

E-Mail Website
Guest Editor
Institute of Chemistry and Technical Electrochemistry, Faculty of Chemical Technology, Poznan University of Technology, Berdychowo 4, 60-965 Poznan, Poland
Interests: production of metal nanostructures (mainly precious metals) using “green chemistry” methods using biopolymers; the use of nanosilver stabilized with biopolymers in concrete technology and in environmental engineering

Special Issue Information

Dear Colleagues,

Nanotechnology is a branch of science which involves the manufacture and testing of structures in which at least one dimension is less than 100 nm. Such particles are called nanoparticles, and these can be classified in terms of their shape, source, and chemical composition.

Nanostructures, in spite of their much smaller size, have the same physicochemical properties as their larger counterparts, but they also have many other features which makes them suitable for a range of new applications in various fields.

Research conducted in the last two decades has clearly demonstrated that the electromagnetic, optical, antibacterial and catalytic properties of metal nanoparticles are very much dependent on their shape and size, as well as their tendency to agglomerate.

This is the reason that there has been growing interest among scientists and researchers in metal nanoparticles.

This Special Issue will also be dedicated to new applications of metal nanoparticles.

We warmly welcome the submission of original research papers and reviews.

Dr. Anna Modrzejewska-Sikorska
Dr. Grzegorz Milczarek
Dr. Emilia Konował
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

 

Keywords

  • metal nanoparticles
  • metal colloids
  • natural polymers
  • NPs properties
  • NPs aplications
  • concrete

Published Papers (1 paper)

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Research

13 pages, 1711 KiB  
Article
Radiotherapy Metastatic Prostate Cancer Cell Lines Treated with Gold Nanorods Modulate miRNA Signatures
by Sílvia Soares, Fátima Aires, Armanda Monteiro, Gabriela Pinto, Isabel Faria, Goreti Sales, Miguel A. Correa-Duarte, Susana Guerreiro and Rúben Fernandes
Int. J. Mol. Sci. 2024, 25(5), 2754; https://doi.org/10.3390/ijms25052754 - 27 Feb 2024
Viewed by 673
Abstract
MicroRNA (miRNA) modulation has been identified as a promising strategy for improving the response of human prostate cancer (PCa) to radiotherapy (RT). Studies have shown that mimics or inhibitors of miRNAs could modulate the sensitivity of PCa cells to RT. In addition, pegylated [...] Read more.
MicroRNA (miRNA) modulation has been identified as a promising strategy for improving the response of human prostate cancer (PCa) to radiotherapy (RT). Studies have shown that mimics or inhibitors of miRNAs could modulate the sensitivity of PCa cells to RT. In addition, pegylated gold nanoparticles have been studied as a therapeutic approach to treat PCa cells and/or vehicles for carrying miRNAs to the inside of cells. Therefore, we evaluated the capacity of hypofractionated RT and pegylated gold nanorods (AuNPr-PEG) to modulate the miRNA signature on PCa cells. Thus, RT-qPCR was used to analyze miRNA-95, miRNA-106-5p, miRNA-145-5p, and miRNA-541-3p on three human metastatic prostate cell lines (PC3, DU145, and LNCaP) and one human prostate epithelial cell line (HprEpiC, a non-tumor cell line) with and without treatment. Our results showed that miRNA expression levels depend on cell type and the treatment combination applied using RT and AuNPr-PEG. In addition, cells pre-treated with AuNPr-PEG and submitted to 2.5 Gy per day for 3 days decreased the expression levels of miRNA-95, miRNA-106, miRNA-145, and miRNA-541-3p. In conclusion, PCa patients submitted to hypofractionated RT could receive personalized treatment based on their metastatic cellular miRNA signature, and AuNPr-PEG could be used to increase metastatic cell radiosensitivity. Full article
(This article belongs to the Special Issue Metal Nanoparticles: From Fundamental Studies to New Applications)
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