Molecular Mechanism Involved in Cancer Metastasis
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: 20 May 2025 | Viewed by 1542
Special Issue Editor
2. LR18ES03 Laboratory of Neurophysiology, Cellular Physiopathology and Valorisation of Biomolecules, Faculty of Science of Tunis, University Tunis El Manar, Tunis 2092, Tunisia
3. Department of Biological Sciences, Faculty of Science of Tunis, University Tunis El Manar, Tunis 2092, Tunisia
Interests: cell death; mitotic catastrophe; genomic instability; metastasis; migration; cancer
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Tumour invasion and metastasis are the major causes of tumour recurrence and patient mortality. Metastasis is a complex process that occurs through sequential steps that include invasion into adjacent tissues, intravasation, transport through the circulatory system, arrest at a secondary site, extravasation, and growth in a secondary organ. However, the role of genetic and biochemical determinants and the molecular mechanism of metastasis remain poorly understood.
The aim of this Special Issue is to investigate and/or discuss the morphological and molecular mechanisms and dynamics in cancer metastasis. We invite authors to submit full-length original and review articles on cancer research in both the in vitro and in vivo testing of tumour tissues to elucidate the metastatic process and to evaluate the therapeutic effects of anticancer drugs and their potential clinical application.
Dr. Mohamed Jemaà
Guest Editor
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Keywords
- cell motility
- cell migration
- spheroid
- metastasis
- extracellular matrix
- cell architecture
- lamellipodia
- epithelial-mesenchymal transition EMT
- videomicroscopy
- confocal microscopy
- animal model
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