Molecular Biomarkers in Cancer and Their Applications 2.0
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 10177
Special Issue Editor
2. Centro de Investigación Biomédica en Red de Cancer (CIBERONC), 28029 Madrid, Spain
Interests: tumor microenvironment; colorectal cancer; cancer-associated fibroblasts; exosomes; migration and invasion; tumor biomarkers
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
A molecular biomarker in cancer is a measurable indicator, including genetic variations, differences in messenger RNA (mRNA) and/or protein expression, post-translational modifications of proteins, metabolite levels, among others. A large amount of literature has demonstrated the potential of different molecular biomarkers for clinical utility. Thus, molecular biomarkers guide disease diagnostics or drug treatment in many settings. Based on their clinical use, they can be classified as diagnostic, prognostic, pharmacodynamic or predictive cancer biomarkers. Currently, the use of liquid biopsy, mainly blood or serum, to identify molecular biomarkers is showing high potential to better understand tumor heterogeneity and tumor molecular behavior in order to identify the best type of treatment.
This Special Issue welcomes original research and review papers. Potential topics include, but are not limited to, the following:
- Determination of new molecular biomarker for patient classification (diagnostic) and for patient survival prediction (prognostic).
- Manuscripts related to molecular biomarkers for treatment efficacy or toxicity (pharmacodynamics and predictive biomarkers).
- Application of molecular biomarkers in the development of novel cancer therapies.
- Large-scale genomic and proteomic analysis for molecular biomarker identification.
- Identification of pathway-specific biomarkers to consider the efficacy of targeted cancer treatments.
- Machine learning studies from large data sets to identify new cancer-related molecular biomarkers.
- Potential application of cancer molecular biomarkers in liquid biopsies.
Dr. Cristina Peña
Guest Editor
Manuscript Submission Information
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Keywords
- molecular biomarker
- liquid biopsy molecular biomarker
- diagnostic predictive molecular biomarkers
- prognostic molecular biomarkers
- pharmacodynamics molecular biomarkers
- predictive molecular biomarkers
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