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The Blood–Brain Barrier and Neuroprotection

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".

Deadline for manuscript submissions: 28 February 2025 | Viewed by 87

Special Issue Editors


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Guest Editor
Department of Surgical Sciences, Akademiska Sjukhuset, Uppsala University, Uppsala, Sweden
Interests: neurotoxicity; anesthesia; brain function; blood-brain barrier; morphology

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Guest Editor
Division of Anesthesiology & Intensive Care Medicine, Department of Surgical Sciences, Uppsala University Hospital, Uppsala University, Uppsala, Sweden
Interests: neurobiology; blood brain barrier (BBB); brain dysfunction

Special Issue Information

Dear Colleagues,

The blood–brain barrier (BBB) plays a regulatory role of the central nervous  system (CNS) in maintaining homeostasis for normal brain function. In acute  or chronic diseases, the BBB breakdown occurs, leading to extravasation of  unwanted substances, e.g., proteins, hormones, toxins, and other harmful  elements, into the brain, resulting in brain pathology. Thus, regulation of  the BBB is one of the critical factors in health and disease. This Special Issue aims to explore the role of the BBB in modifying the disease processes using conventional and nanoformulations to maintain the integrity of the BBB in neurodegenerative diseases in pre-clinical and clinical conditions. Involvement of the molecular mechanisms of BBB integrity and repair will be discussed in various acute and chronic neurodegenerative diseases. We hope that this Special Issue will widen our understanding of BBB and brain diseases and enhance our knowledge of therapy.

Dr. Aruna Sharma
Prof. Dr. Hari Shanker Sharma
Guest Editors

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Keywords

  • blood–brain barrier
  • neurodegenerative diseases
  • nanoformulations
  • drug development
  • delivery systems

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Published Papers

This special issue is now open for submission.
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