Inflammation and Cellular Senescence in Age-Related Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 20 May 2025 | Viewed by 1862
Special Issue Editors
Interests: ageing; age-related diseases; centenarians; immunogenetics; immunosenescence; inflammation; longevity; successful ageing; unsuccessful ageing
Special Issues, Collections and Topics in MDPI journals
Interests: autoimmunity; immune response; immunogenetics; immunosenescence; inflammaging; immunopathology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
As is well known, life expectancy has increased worldwide. Unfortunately, this increase in lifespan is not accompanied in most older individuals by an increase in healthy life expectancy, the so-called health-span. The main cause of this disability is the onset of ageing-related diseases (ARDs), and it is time to seriously address how to prevent or at least postpone the appearance of these debilitating diseases. Ageing in good health would result in a net gain for society in social, economic, and health terms. The purpose of this Special Issue is to expand our knowledge in the fields of ARDs. Its ambition is to publish articles that explore the multiple factors responsible for the etiopathogenesis and pathophysiology of these diseases, with the aim of better prevention or treatment (and a particular focus on the role of inflammatory processes and cellular senescence). Contributions may come from all basic and applied disciplines that research these processes. Naturally, the role of the exposome in determining these diseases may also be analyzed, as well as possible preventive interventions. By disseminating research on these topics, conducted either on humans or models, this Special Issue aims to create interdisciplinary connections, thereby facilitating a comprehensive understanding of ARDs, and hence of their prevention.
Prof. Dr. Calogero Caruso
Prof. Dr. Giuseppina Candore
Guest Editors
Manuscript Submission Information
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Keywords
- age-related diseases
- exposome
- prevention
- pathophysiology
- pathogenesis
- inflammation
- senescence
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