Epigenetics of Metabolic Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Genetics and Genomics".
Deadline for manuscript submissions: 20 September 2025 | Viewed by 255
Special Issue Editor
2. Institute of Agri-Food and Life Sciences, University Research and Innovation Centre, Hellenic Mediterranean University, 71003 Heraklion, Greece
Interests: epigenetics; DNA methylation; biomarker; classifier; liquid biopsy; metabolic disease; diabetes; AutoML
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Metabolic diseases, including obesity, type 2 diabetes, non-alcoholic fatty liver disease (NAFLD), cardiovascular diseases, etc., as well as metabolic syndrome, represent growing challenges in global health. Recent advances in epigenetics have unveiled critical molecular mechanisms linking genetic and environmental factors to metabolic dysregulation and the onset and progression of various metabolic disorders. Epigenetic modifications, such as DNA methylation, histone modifications, and non-coding RNA regulation, play key roles in metabolic homeostasis and disease progression.
This Special Issue of IJMS, “Epigenetics of Metabolic Diseases” aims to highlight cutting-edge research on the molecular epigenetic mechanisms underlying metabolic diseases. We invite original research articles and reviews focusing on how epigenetic changes influence metabolic pathways, gene expression, and disease susceptibility. Studies utilizing high-throughput sequencing, single-cell epigenomics, and mechanistic insights into epigenetic regulators are particularly welcome. We encourage multi-omics approaches integrating epigenomics, transcriptomics, and metabolomics to deepen our understanding of metabolic disease pathogenesis. Through this Special Issue, we aim to advance the field of epigenetics in metabolism and foster new perspectives for precision medicine in metabolic disorders.
Dr. Makrina Karaglani
Guest Editor
Manuscript Submission Information
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Keywords
- epigenetics
- metabolic diseases
- DNA methylation
- histone modifications
- non-coding RNAs
- obesity
- diabetes
- metabolic syndrome
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