Molecular Mechanisms and Therapies for Metabolic-Associated Fatty Liver Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 15 January 2025 | Viewed by 1977
Special Issue Editor
Special Issue Information
Dear Colleagues,
Metabolic-associated fatty liver disease (MAFLD), previously termed non-alcoholic fatty liver disease, is becoming the leading cause of liver cirrhosis and hepatocellular carcinoma globally. The recent change in nomenclature to MAFLD refocuses the importance of this disease entity on its metabolic underpinnings and may help to spur a paradigm shift in the approach to its prevention and treatment. Previously, a prospective study in adult MAFLD patients showed that both liver fibrosis stages F3 and F4 are associated with death due to liver disease. Currently, there is no approved pharmacological treatment for MAFLD. In this Special Issue, reviews and articles will demonstrate the complexity of the various metabolic pathways and genetic polymorphisms associated with MAFLD. Topics related to the molecular mechanism, diagnosis, prevention, and treatment are welcome.
Prof. Dr. Yi-Ming Arthur Chen
Guest Editor
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Keywords
- metabolic-associated fatty liver disease
- MAFLD
- metabolic dysfunction-associated steatohepatitis
- MASH
- molecular mechanism
- genetic polymorphism
- individualized medicine
- prevention
- new drug development
- health supplements
- diagnosis
- epidemiology
- lifestyle
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