Molecular Diagnostic Strategies for Prediction and Prognosis of Gastric Cancer
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: closed (20 April 2024) | Viewed by 5789
Special Issue Editor
Special Issue Information
Dear Colleagues,
Gastric cancer is the fifth most common cancer and the third cause of cancer death. The clinical outcomes of these patients are not encouraging, with a low survival rate of 5 years. Often, the disease is diagnosed at advanced stages and this negatively affects patients’ outcomes. Intra-tumoural and inter-tumoural heterogeneity is a feature of gastric cancer, which leads to diagnostic and therapeutic challenges.
Currently, diagnostic typing is based on immunohistochemistry evaluation of the expression of a few specific biomarkers that are correlated with disease prognosis. Moreover, to date, no validated biomarkers that are predictive of the treatment response to targeted therapies are available, with the exception of HER2 overexpression and MSI status. Taking into account this scenario, there is an urgent need to develop new predictive and prognostic diagnostic strategies for gastric cancer patients’ management.
For this reason, this Special Issue will embrace papers that reveal new diagnostic molecular approaches that support pathological diagnosis with high specificity and sensitivity and studies that assess the role of liquid biopsy as a new valuable diagnostic method. In addition, new manuscripts that investigate biomarkers mirroring the prognosis or response to therapy will be highly valued. All these studies will have a significant impact on these patients’ outcomes in the era of personalized medicine.
In this Special Issue, original articles and reviews are both welcome.
Dr. Matteo Curtarello
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- prognostic biomarker
- predictive biomarker
- gastric cancer
- molecular diagnostic strategy
- solid biopsy
- liquid biopsy
- real-time PCR
- digital PCR
- next-generation sequencing
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.