Trends in Allergy and Autoimmunity: Pathogenesis, Biomarkers, and Treatment
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".
Deadline for manuscript submissions: 30 November 2024 | Viewed by 16
Special Issue Editor
Interests: immunology; autoimmunity; allergic and inflammatory diseases; autoimmune diseases; allergen immunotherapy; biological therapies; bronchial asthma; fibroblasts; hereditary angioedema; bradykinin; VEGF
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Allergy and autoimmunity result from the dysregulation of the immune system and sometimes intersect. Many molecular and cellular actors have been reported to participate in both allergic inflammation and autoimmune disorders, revisiting the old-fashioned concept that Th1- and Th2-related diseases could not coexist. In addition, in recent years, the application of new technologies such as “omics”, machine learning, and artificial intelligence have led to immense progress in understanding the pathogenesis and identification of therapeutic targets for allergic and autoimmune diseases. However, despite the significant advances in diagnosis and treatment in recent decades, some challenges still exist. This broad research theme aims to explore the possible molecular connection between allergy and autoimmunity as two faces of the same coin and collect the most recent advances in targeted therapies. This collection will also promote personalized medicine, in which diseases are prevented and treated according to individual variability in genes, phenotypical features, environment, and lifestyle for each group of patients. This Special Issue will include original research, meta-analyses, and review articles focusing on inflammatory cell biology, characterization of their subtypes, novel biomarkers of activation, and evaluation of gene expression and protein levels of inflammatory and pro-resolving mediators. We also welcome articles on the recent applications of routine laboratory parameters and instrumental techniques for assessing disease severity and organ involvement in allergic and autoimmune diseases. Finally, we encourage the submission of manuscripts exploring treat-to-target therapy, including monoclonal antibodies and small molecules for immune-mediated disorders.
We look forward to receiving your contributions to this Special Issue.
Dr. Ilaria Mormile
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- allergy
- autoimmunity
- autoimmune diseases
- asthma
- allergic rhinitis
- urticaria
- inflammation
- molecular pathway
- biomarkers
- target therapy
