Role of Cytokines in Cancer Metastasis Studies
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: closed (15 January 2023) | Viewed by 2858
Special Issue Editor
2. School of Oral Hygiene, College of Oral Medicine, Taipei Medical University, Taipei City 11031, Taiwan
Interests: pharmacology cancer; tumor metastasis to bone; cancer
Special Issue Information
Dear Colleagues,
Cytokines, mixture of multifunctional mediators, not only regulate cell-to-cell communication but also involve primary cancer colonizing at a secondary microenvironment and tumor-stroma crosstalk in cancer pathogenesis. The dual functionality of cytokines in cancer metastases may display both tumor-promoting and tumor-suppressive capabilities. Therefore, further exploration of the regulatory mechanisms that control the protumor and antitumor activities of cytokines in the setting of cancer metastases is warranted. This will allow for the design of therapeutic molecules that can effectively target the tumorigenic pathways in patients with cancer metastases. Early diagnosis is crucial for the optimal treatment of patients with cancer metastases. Therefore, understanding the molecular underpinnings that govern the cancer cell-cytokine interactions in the setting of cancer metastases is crucial for the development of more accurate diagnostics and efficacious therapies.
Dr. Ju-Fang Liu
Guest Editor
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Keywords
- cytokines
- cancer
- metastasis
- migration
- EMT
- cell signaling