Bioactive Compounds and Health 2.0

Dear Colleagues,

The last decade has been marked by an intense scientific interest in the use of bioactive compounds of various origins and their potential effects on human health, both from researchers and industry. These bioactive compounds have similar cellular targets to those of the new drugs developed by pharmaceutical companies. For example, the Food and Drug Administration (FDA) showed that 40% of the approved molecules are natural compounds or inspired by them, of which 74% are used in anticancer therapy. Pleiotropic pharmaceutical activities are used in fields such as cancer, inflammation, arthritis, cardiovascular diseases, auto-immune diseases, eye diseases, and many other domains. Among these bioactive compounds, polyphenols, fatty acids such as omega-3, oil extracts, and marine compounds could be candidates of choice to exert a preventive action against many of the evils of our century, and could act as therapeutic adjuvants.

This Special Issue follows the first edition, published in the International Journal of Molecular Sciences, which highlighted the current knowledge of various bioactive compounds and their derivatives, as well as the latest scientific advances in various domains, including metabolic diseases, cancers, degenerative age-related diseases, ocular diseases, and inflammatory/immune pathologies. I cordially invite authors to contribute their original articles as well as review articles that will provide readers of the International Journal of Molecular Sciences with updated and new perspectives on bioactive molecules and their derivatives, which could establish a new interest in the development of natural compounds for the following health subtopics: the structure–activity relationships of natural bioactive compounds; bioactive molecules and cancers; bioactive molecules and degenerative diseases; bioactive molecules and ocular diseases; bioactive molecules and inflammatory diseases; bioactive molecules and metabolic disorders; bioactive molecules and immune disorders.

Prof. Dr. Dominique Delmas
Guest Editor

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• polyphenols
• polyunsaturated fatty acids
• oil extracts
• marine products
• molecular mechanisms
• signaling pathways
• degenerative diseases
• cancers
• prevention
• inflammation/immunity