Molecular Research Targeting Sarcomas: Diagnosis and Therapeutics
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (15 April 2024) | Viewed by 2377
Special Issue Editor
Special Issue Information
Dear Colleagues,
Malignant bone and soft tissue tumors (sarcomas) are relatively common neoplasms. Some of them arise typically in pediatric patients. In general, low-grade tumors show a tendency for local recurrence and are often difficult to resect surgically depending on the location. In addition, low-grade sarcomas do not usually show a good response to neoadjuvant treatments. High-grade sarcomas are very aggressive and have a tendency for distant metastasis, and although they show a better response to cancer treatment, they usually develop treatment resistance over time, and overall survival is shorter. New therapeutic targets are needed that can potentially avoid the spread and progression of the disease. New insights into tumor biology, histopathology, immunophenotype and molecular alterations of bone/soft tissue tumor are needed in order to better understand the clinical outcome and to find potential therapeutic targets including immunotherapy.
The Special Issue, entitled "Molecular Research Targeting Sarcomas: Diagnosis and Therapeutics", aims to provide a research platform for the collection of the latest original and review articles covering immunohistochemical and molecular biological studies of factors related to the control of bone and soft tissue malignant tumors and action mechanisms of anti-sarcoma targets.
Dr. Francisco Giner
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Keywords
- sarcoma
- molecular alterations
- therapeutic targets
- immunotherapy
- research platform
