New Insights into Diet, Gut Microbiota and Human Health
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Microbiology".
Deadline for manuscript submissions: 20 January 2025 | Viewed by 8048
Special Issue Editor
Interests: functional gastrointestinal disorders; malabsorption syndrome; celiac disease; irritable bowel syndrome; osteoporosis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Mounting evidence supports the role of diet in modulating the composition and metabolic activity of the human gut microbiota, which, in turn, can have a tremendous impact on the overall health of the host. This impact can be beneficial or detrimental, depending on the relative abundance of beneficial and harmful species of constituent microbial populations. Emerging studies demonstrating that diet can modulate host–microbe interactions signal promising future therapeutic approaches. However, understanding the mechanisms of the effects of diet in modulating the gut microbiota is important to define novel therapeutic modalities. Most dietary nutrients are absorbed in the upper small intestine. However, there are an extremely limited number of studies focused on the impact of small intestinal microbiota on host health, a topic which should be addressed in future studies.
The focus of this Special Issue, therefore, is to publish featured articles (review articles, original research articles, communications, and commentaries) aimed at: (1) elucidating the mechanistic details of the diet–microbiota–host cross-talk occurring in different segments of the gut that, ultimately, determine the health and/or disease state of the host, and compiling published studies on this theme; and (2) critically discussing the thoughts, controversies and research gaps in this field that should be addressed in future research.
Dr. Michele Di Stefano
Guest Editor
Manuscript Submission Information
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Keywords
- gut microbiota
- probiotics and prebiotics
- intestinal epithelial cells
- inflammation
- infection
- microbial metabolites
- nutrient absorption and metabolism
- epithelial barrier function
- immunomodulation
- nutrient sensing and gut hormone secretion
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