Hepatocyte Growth Factor (HGF)

Dear Colleagues,

Hepatocyte growth factor (HGF), also known as hepatopoietin-A (HPTA), scatter factor (SF), and fibroblast-derived tumor cytotoxic factor (F-TCF), is a pleiotropic growth factor that is secreted mainly from mesenchymal cells and acts on epithelial cells, endothelial cells, and other types of cells. The receptor of HGF is the product of c-met proto-oncogene with tyrosine kinase activity that mediates the transduction of multiple biological signals of HGF. Since HGF was purified and HGF cDNA was molecularly cloned in the late 1980s, extensive studies have been carried out in the fields of not only tissue regeneration but also cell biology, tumor biology, neurology, immunology, and others. 

This Special Issue of the International Journal of Molecular Sciences will focus on recent advances in “Hepatocyte Growth Factor (HGF)” research, including new insights into liver regeneration, activation, biological and pharmacological activities, signaling pathways, structure-function relationships, regulation of expression, therapeutic and diagnostic applications, and other aspects of HGF. Original research papers and review articles relevant to those topics are welcome.

Prof. Emeritus Dr. Eiichi Gohda
Prof. Emeritus Dr. Hirohito Tsubouchi
Guest Editors

The first round of submission deadline: 30 November 2018

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