Sexual Dimorphism in Cancers: Gender-Related Mechanisms in Cancer Development
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: closed (30 January 2024) | Viewed by 1856
Special Issue Editor
Special Issue Information
Dear Colleagues,
Sexual dimorphism is a clear but mostly neglected phenotype for most human non-reproductive cancers, and investigations of the underlying mechanisms are barely conducted. Hormonal aspects have usually been considered the major drivers of sex differences in tumors; however, more recently other pathways, such as epigenetics, stem cell renewal, immunity, or metabolism, have been highlighted as important contributors.
The purpose of this Special Issue of IJMS is to explore how sex and gender issues may act in influencing the lifestyle, physiology, cell proliferation or differentiation control, and molecular pathways that underpin tumor development and patient responses in men versus women. Moreover, sex-specific cancer traits that impact diagnoses, clinical practice, patient care, and responses to standard treatments should be highlighted to help precision medicine. This Special Issue will also focus on how tumor-related processes can be determined or modified by sex-dependent issues. The Special Issue will cover studies considering patient cohort analyses, animal models, biochemical and/or experimental studies investigating molecular pathways, and reviews exploring new insights into the impacts of sex and gender on cancers.
Dr. Helene Dumond
Guest Editor
Manuscript Submission Information
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Keywords
- gender and sex differences
- tumor biology
- precision medicine
