Bacterial Infections and Immunodeficiency: New Insights into an Old Story
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".
Deadline for manuscript submissions: closed (30 May 2020) | Viewed by 15960
Special Issue Editor
Interests: primary immunodeficiencies; vaccines; anti-infectious immunity; mucosal immunity
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The aim of this update on bacterial infections and primary immunodeficiency (PID) is to provide new insights into the current state of knowledge on the interaction between microbes and humans. PID diseases were first recognized in patients with an increased susceptibility to bacterial infections resulting from defined genetic defects of the immune system. The susceptibility might be to many or few pathogens and might cause a spectrum of diseases ranging from mild to life-threatening infections. In recent years, our knowledge of the pathogenesis of abnormalities of the interplay between bacteria and the immune protective mechanisms has increased due the growth number of patients recognized as affected by a PID disease, the identification of new PID entities, better knowledge of the local immunity, bacterial colonization and microbiota composition, and new information on bacterial virulence factors. In the light of these recent data, the bacteria–human relationship needs to be periodically updated to provide information for future therapeutic strategies.
Prof. Dr. Isabella Quinti
Guest Editor
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Keywords
- Primary immune deficiencies
- Genetic defects
- Immune pathways
- Bacterial infections
- Bacterial susceptibility
- Bacterial virulence
- Immune defects
- Bacterial colonization
- Microbiota
- Anti-microbial treatments
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