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Advanced in Functional Hybrid Nanomaterials
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Advanced in Functional Hybrid Nanomaterials

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Nanoscience".

Deadline for manuscript submissions: 20 January 2025 | Viewed by 3521

Special Issue Editor

Dr. Maria Rosaria Plutino

E-Mail Website
Guest Editor
Institute for the Study of Nanostructured Materials, ISMN–CNR, Palermo, c/o Department ChiBioFarAm, University of Messina, 98166 Messina, Italy
Interests: materials chemistry; green chemistry; nanotechnology; environmental remediation; advanced materials; functional coating; colloidal nanoparticles; smart and hi-tech textiles; (waste)water treatment; multifunctional hybrid materials and nanocomposites; sensing technologies; bio-based blended polymers; circular economy
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

New nanotechnologies and nanomaterials are currently being used in a wide variety of applications due to their unique properties such as large surface area (surface/volume ratio), reactivity, size effects, and catalytic features, placing them as suitable candidates to address different challenges. In this context, they can be easily chemically modified, functionalized, and embedded in various polymeric and bio-polymeric blends to generate innovative hybrid materials or nanocomposites with enhanced chemical, physical, and mechanical characteristics, but also functional properties. The objective of this Special Issue is to present modern innovative approaches to rational designs, concerning the development of advanced nanostructured, novel, stimuli-responsive and also eco-friendly materials that can be used as surface coatings or in various forms, exploiting different (multi)functional properties, i.e., anti-fouling, antibacterial, hydrophobic/hydrophilic, flame retardant, drug release, biological and chemical molecule sensing, up to the absorption and degradation of environmental pollutants. Therefore, leading to a contribution with to a multitude of application sectors including blue-growth, building, cultural heritages, smart and technical textiles, biomedicine, and environmental sensing and remediation.

Dr. Maria Rosaria Plutino
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nano-hybrids
  • innovative advanced materials
  • rational design
  • sustainable materials
  • eco-friendly approaches
  • stimuli-responsive materials
  • sol-gel technology
  • functional coatings
  • sustainable nanotechnology

Published Papers (2 papers)

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Research

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15 pages, 4581 KiB  
Article
A New Tailored Nanodroplet Carrier of Astaxanthin Can Improve Its Pharmacokinetic Profile and Antioxidant and Anti-Inflammatory Efficacies
by Kumudesh Mishra, Nadin Khatib, Dinorah Barasch, Pradeep Kumar, Sharon Garti, Nissim Garti and Or Kakhlon
Int. J. Mol. Sci. 2024, 25(14), 7861; https://doi.org/10.3390/ijms25147861 - 18 Jul 2024
Viewed by 326
Abstract
Astaxanthin (ATX) is a carotenoid nutraceutical with poor bioavailability due to its high lipophilicity. We tested a new tailored nanodroplet capable of solubilizing ATX in an oil-in-water micro-environment (LDS-ATX) for its capacity to improve the ATX pharmacokinetic profile and therapeutic efficacy. We used [...] Read more.
Astaxanthin (ATX) is a carotenoid nutraceutical with poor bioavailability due to its high lipophilicity. We tested a new tailored nanodroplet capable of solubilizing ATX in an oil-in-water micro-environment (LDS-ATX) for its capacity to improve the ATX pharmacokinetic profile and therapeutic efficacy. We used liquid chromatography tandem mass spectrometry (LC-MS/MS) to profile the pharmacokinetics of ATX and LDS-ATX, superoxide mutase (SOD) activity to determine their antioxidant capacity, protein carbonylation and lipid peroxidation to compare their basal and lipopolysaccharide (LPS)-induced oxidative damage, and ELISA-based detection of IL-2 and IFN-γ to determine their anti-inflammatory capacity. ATX and LDS-ATX corrected only LPS-induced SOD inhibition and oxidative damage. SOD activity was restored only by LDS-ATX in the liver and brain and by both ATX and LDS-ATX in muscle. While in the liver and muscle, LDS-ATX attenuated oxidative damage to proteins and lipids better than ATX; only oxidative damage to lipids was preferably corrected by LDS-ATX in the brain. IL-2 and IFN-γ pro-inflammatory response was corrected by LDS-ATX and not ATX in the liver and brain, but in muscle, the IL-2 response was not corrected and the IFN-γ response was mitigated by both. These results strongly suggest an organ-dependent improvement of ATX bioavailability and efficacy by the LDS-ATX nanoformulation. Full article
(This article belongs to the Special Issue Advanced in Functional Hybrid Nanomaterials)
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Review

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33 pages, 14911 KiB  
Review
Sustainable Secondary-Raw Materials, Natural Substances and Eco-Friendly Nanomaterial-Based Approaches for Improved Surface Performances: An Overview of What They Are and How They Work
by Silvia Sfameni, Giulia Rando and Maria Rosaria Plutino
Int. J. Mol. Sci. 2023, 24(6), 5472; https://doi.org/10.3390/ijms24065472 - 13 Mar 2023
Cited by 14 | Viewed by 2737
Abstract
To meet modern society’s requirements for sustainability and environmental protection, innovative and smart surface coatings are continually being developed to improve or impart surface functional qualities and protective features. These needs regard numerous different sectors, such as cultural heritage, building, naval, automotive, environmental [...] Read more.
To meet modern society’s requirements for sustainability and environmental protection, innovative and smart surface coatings are continually being developed to improve or impart surface functional qualities and protective features. These needs regard numerous different sectors, such as cultural heritage, building, naval, automotive, environmental remediation and textiles. In this regard, researchers and nanotechnology are therefore mostly devoted to the development of new and smart nanostructured finishings and coatings featuring different implemented properties, such as anti-vegetative or antibacterial, hydrophobic, anti-stain, fire retardant, controlled release of drugs, detection of molecules and mechanical resistance. A variety of chemical synthesis techniques are usually employed to obtain novel nanostructured materials based on the use of an appropriate polymeric matrix in combination with either functional doping molecules or blended polymers, as well as multicomponent functional precursors and nanofillers. Further efforts are being made, as described in this review, to carry out green and eco-friendly synthetic protocols, such as sol–gel synthesis, starting from bio-based, natural or waste substances, in order to produce more sustainable (multi)functional hybrid or nanocomposite coatings, with a focus on their life cycle in accordance with the circular economy principles. Full article
(This article belongs to the Special Issue Advanced in Functional Hybrid Nanomaterials)
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