Recent Advances on Bioreceptors and Nanomaterial-Based Biosensors
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".
Deadline for manuscript submissions: closed (20 June 2024) | Viewed by 598
Special Issue Editor
Interests: The evolutionarily directed affinity of nucleic acids and antibodies towards the corresponding analytes (complementary sequences, antigens) makes them applicable, among others, as receptors for affinity biosensor sensing layers. Molecular recognition taking place in a few nanometer interfacial space (surface/solution) translates into a very strong response of biological sensors and obtaining low detection limits or very high sensitivity of conducted analyses. Research topics include, among others, the construction and analysis of receptor layers of affinity biosensors (nucleic acids, including aptamers and antibodies) as well as the construction of ready-made sensor solutions, also on substrates manufactured using printed electronics technology. Such solutions, due to their high degree of miniaturization, possibility of simultaneous detection of several analytes, low cost or freedom of production scalability, have a high degree of applicability through integration into modern microfluidic devices and ulti
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Special Issue Information
Dear Colleagues,
The need for selective detection and determination of low concentrations of certain analytes in the shortest possible time of analysis has prompted continuous efforts aimed at the design and construction of new microanalytical devices. Of much interest in this area are chemical sensors, along with their specific type of biological-origin components in the analyte-identifying layer, called biosensors.
Depending on the composition of the above mentioned receptor layer, it is possible to detect and determine almost any compound of interest, from simple ions to organic compounds, peptides, proteins nucleic acids or even whole cells. Because of the available versatile organic synthesis methods, which provide us with the possibility to conjugate chosen biological molecules or adjust their sequence or structure, it is possible, on the one hand, to increase their specificity towards chosen analyte, and on the other, to increase their resistance to environmental conditions, making them significantly more useful in real-life applications. This is further supported by developed new nanomaterials (nanoparticles, graphene, quantum dots, etc.). They can be used as markers, substrates or carriers for chosen receptors, which allows for an almost unlimited elaboration of bio(sensors) with analytical parameters specifically adjusted to the given application. Such features make these devices very attractive for modern analytical methods.
This Special Issue of IJMS is focused on recent molecular advances in biosensors. We welcome submissions of research articles, reviews, etc.
Dr. Robert Ziółkowski
Guest Editor
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Keywords
- biosensor
- nanomaterials
- microfluidic devices
- mems
- detection techniques
- aptamers
- antibodies
