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Investigating Host-Parasite Interactions for the Discovery of Novel Therapies and Vaccine Targets

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".

Deadline for manuscript submissions: 31 January 2025 | Viewed by 47

Special Issue Editor


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Guest Editor
Institute for Hygiene and Microbiology, Julius-Maximilians-Universität Würzburg, Josef-Schneider-Str. 2, 97080 Würzburg, Germany
Interests: infectious disease; immunology; host-pathogen interactions; tuberculosis; vaccines; fungal infection; leishmaniasis; helminth infection; IL-4 receptor alpha; TGF-beta; activin A
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Special Issue Information

Dear Colleagues,

Parasite infections are a significant global health problem, affecting millions of people worldwide, particularly in sub-tropical and tropical regions and in communities with limited access to clean water and sanitation. Helminths (e.g., Schistosoma, Ascaris, Trichuris), unicellular eukaryotes (e.g. Plasmodium, Leishmania, Trypanosoma), protozoans (e.g., Toxoplasma) and athropods (e.g.,  mosquitoes, ticks) represent diverse groups of organisms that can cause a wide range of diseases, from mild to life-threatening. On the World Health Organization’s list of top 20 priority neglected tropical diseases, 12/20 are caused by parasites.

Understanding the intricate molecular interactions between hosts and parasites is crucial for the development of novel therapies and vaccine targets. Parasites are in a dependent relationship with their hosts and have evolved mechanisms to avoid or suppress host immune responses over millions of years.

This Special Issue aims to highlight recent advancements in the field of host–parasite interactions, with a particular focus on molecular studies that could inform the development of novel drug and vaccine targets. We are particularly interested in research articles, but reviews will also be considered if they have something new to contribute to the field. We invite contributions from researchers working on a diverse range of host-parasite systems, including but not limited to, the following:

  • Soil-transmitted helminths;
  • Schistosomiasis;
  • Malaria;
  • Leishmaniasis;
  • Trypanosomiasis;
  • Echinococcus;
  • Anisakiasis. 

Dr. Natalie Nieuwenhuizen
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • parasites
  • host-pathogen interactions
  • helminths
  • worms
  • protozoans
  • leishmania
  • malaria
  • schistosomiasis
  • trypanosomiasis
  • ascariasis
  • anisakiasis
  • vectors
  • mosquitoes
  • ticks
  • neglected tropical diseases

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Published Papers

This special issue is now open for submission.
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