Biomarkers in Cancer Immunology
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".
Deadline for manuscript submissions: 31 December 2024 | Viewed by 1767
Special Issue Editor
Interests: biochemistry; exosomes; DNA damage
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Cilleagues,
Cancer immunotherapy is now recognized as one of the main pillars of treatment alongside surgery, radiation, and chemotherapy. Targeted therapy and immunotherapy in combination are considered the ideal strategy for treating metastatic cancer, as this combination can eliminate primary tumors and induce host immunity to control distant metastases. Cancer immunotherapy harnesses the power of the host immune system to fight against cancer. Several types of immunotherapy, including adoptive cell transfer (ACT) and immune checkpoint inhibitors (ICIs), have achieved durable clinical responses, but their efficacies vary, and only subsets of cancer patients can benefit from them. Immune infiltrates in the tumor microenvironment (TME) have been shown to play a key role in tumor development and will affect the clinical outcomes of cancer patients. Comprehensive profiling of tumor-infiltrating immune cells would shed light on the mechanisms of cancer-immune evasion, thus providing opportunities for the development of novel therapeutic strategies. Importantly, Chimeric antigen receptor T (CAR-T) cell therapy achieved extraordinary results in antitumor treatments, especially against hematological malignancies, where it leads to remarkable, long-term antineoplastic effects with higher target specificity. Biomarkers play an important role in toxicity, relapse assessment, and efficacy prediction, and can be implicated in clinical applications of cancer immunotherapy and in establishing safe and efficacious personalized medicine. Therefore, improving our understanding of the progress in cancer immunotherapy may facilitate the elucidation of immune cell modulation in tumor progression.
Dr. Wioletta Olejarz
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- immunotherapy
- adoptive cell transfer
- CAR-T cells
- immune checkpoint inhibitors
- tumor microenvironment
- extracellular vesicles
- biomarkers
- miRNA
- DNA
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.
