Molecular Advances in Endometrial Cancer
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: 20 March 2025 | Viewed by 27
Special Issue Editor
Special Issue Information
Dear Colleagues,
Endometrial cancer, the most common gynecologic malignancy, remains a significant global health concern despite advancements in diagnosis and treatment. Recent molecular and genetic insights, particularly from Cancer Genome Atlas (TCGA) data, have significantly enhanced our understanding of the disease's diverse biological subtypes and their prognostic implications. This has led to the development of the 2023 FIGO staging system, aimed at better defining prognostic groups and guiding appropriate therapeutic approaches. Another crucial advancement in endometrial cancer is fertility-sparing treatment. The 2023 ESGO/ESHRE/ESGE guidelines have emphasized the importance of preserving fertility for eligible patients, providing guidance on work-up, management, and follow-up. Finally, with the increasing number of endometrial cancer patients achieving long-term survival due to timely diagnosis and medical advancements, understanding post-treatment quality of life and sexual functioning becomes fundamental.
This Special Issue aims to highlight recent breakthroughs and emerging trends in the field of endometrial cancer research. By fostering a platform for the dissemination of novel findings, we aim to advance our understanding of the disease, improve patient outcomes, and inform future clinical practices.
In this Special Issue, we welcome original research articles and reviews that gather the latest scientific advancements on endometrial cancer. Research areas may include, but are not limited to, the following:
- Etiology, risk factors, and early detection: Exploring the underlying causes and predisposing factors associated with endometrial cancer development and investigating innovative approaches for early diagnosis, including biomarker discovery and advanced imaging techniques.
- Molecular profiling and targeted therapies: Characterizing the molecular landscape of endometrial cancer and exploring the potential of targeted treatments, including immunotherapy and immune checkpoint inhibitors.
- Surgical management and fertility-sparing treatment: Discussing advancements in surgical techniques and exploring strategies for preserving fertility in women with endometrial cancer.
- Quality of life and survivorship: Addressing the physical, psychological, and social challenges faced by patients with endometrial cancer, ensuring a comprehensive and supportive approach to care.
We look forward to receiving your contributions.
Dr. Ursula Catena
Guest Editor
Manuscript Submission Information
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Keywords
- endometrial cancer
- risk factors
- early detection
- molecular profiling
- targeted therapy
- immunotherapy
- surgical management
- fertility-sparing treatment
- quality of life
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