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Herpes Simplex Virus: Immunity, Pathogenicity, Immune Escape Mechanisms, and Antiviral Strategies

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".

Deadline for manuscript submissions: 31 January 2025 | Viewed by 49

Special Issue Editor


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Guest Editor
Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, V.le F. Stagno d’Alcontres 31, 98166 Messina, Italy
Interests: immunological aspects of herpesvirus infections; role of PCD in pathogenesis of viral infections; functional studies of UL49 and UL41 structural proteins, during HSV replication; involvement of ERK1 pathway in the modulation of CCR5 receptor; studies of cyclodextrins carriers as drug or nucleic acid delivery system for cancer therapy, imaging and for antiviral treatment
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Special Issue Information

Dear Colleagues,

The Herpes Simplex Virus (HSV) represents a significant global health challenge due to its ability to establish lifelong latency, evade the host immune system, and cause various diseases, from mild skin infections to severe neurological disorders. This Special Issue aims to consolidate current research on the intricate interplay between HSV and the host immune system, focusing on the epigenetic mechanisms regulating HSV infection and latency, as well as exploring the multifaceted roles of tegument proteins to identify the molecular mechanisms underlying HSV pathogenesis and facilitate the development of novel antiviral strategies. Through this comprehensive approach, this Special Issue seeks to advance our understanding of HSV biology and contribute to the development of more effective therapeutic interventions.

Prof. Dr. Maria Teresa Sciortino
Guest Editor

Manuscript Submission Information

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Keywords

  • herpes simplex virus (HSV)
  • latency
  • immune evasion
  • tegument proteins
  • epigenetic mechanisms
  • viral pathogenesis
  • antiviral strategies
  • molecular mechanisms
  • therapeutic interventions

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Published Papers

This special issue is now open for submission.
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