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Luminescent Dyes as Tools for Biological and Medical Applications

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".

Deadline for manuscript submissions: closed (20 December 2024) | Viewed by 1411

Special Issue Editors


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Guest Editor
Dipartimento di Scienze Chimiche Biologiche Farmaceutiche ed Ambientali (CHIBIOFARAM), Università degli Studi di Messina, 98166 Messina, Italy
Interests: organic molecules; porphyrin derivatives; luminescent dyes; supramolecular chemistry
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Dipartimento di Scienze Chimiche Biologiche Farmaceutiche ed Ambientali (CHIBIOFARAM), Università degli Studi di Messina, 98166 Messina, Italy
Interests: organic synthesis; luminescent probes; carbohydrates; BODIPY; curcumin
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Biosensing and bioimaging are powerful biomedical investigation methods used to aid the interpretation of biological and pathological processes in living systems at the molecular level. Bioimaging is an optical form of biosensing used to create non-invasive, visual representations of biological processes in cells, tissues and anatomy that can help advance the understanding of biology and improve the diagnosis and treatment of human disease. Regardless of the kind of luminescent molecule, a nanostructure, small organic skeleton or an inorganic complex can be seen as promising material for the development of new imaging probes.

Therefore, this Special Issue is addressed to authors who would like to communicate their work on luminescent dyes and materials as biological tools for the detection, monitoring and tracking of biologically important species, as well as for biomedical applications such as drug delivery, cancer diagnosis and treatment, genomics, photo dynamic therapy, etc., promoting interdisciplinary studies at the interface of physics, chemistry, biology, and pharmaceutical and medical sciences.

Dr. Chiara Maria Antonietta Gangemi
Prof. Dr. Paola Bonaccorsi
Guest Editors

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Keywords

  • luminescence
  • biomedicine
  • biology
  • biosensing
  • bioimaging
  • nanostructures
  • small organic molecules
  • inorganic complexes

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Published Papers (1 paper)

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Research

9 pages, 1293 KiB  
Communication
Kinetic Study of Coprinus cinereus Peroxidase-Catalyzed Oxidation of 2,2′-Dihydroxyazobenzene
by Rūta Ivanec-Goranina
Int. J. Mol. Sci. 2024, 25(2), 828; https://doi.org/10.3390/ijms25020828 - 9 Jan 2024
Cited by 2 | Viewed by 1009
Abstract
Azo dyes are of concern due to their harmful effects on the environment and human health. The oxidation of 2,2′-dihydroxyazobenzene (DHAB) catalyzed with recombinant Coprinus cinereus (rCiP) peroxidase was investigated. The kinetic measurements were performed using the spectrophotometric and fluorimetric methods. The dependences [...] Read more.
Azo dyes are of concern due to their harmful effects on the environment and human health. The oxidation of 2,2′-dihydroxyazobenzene (DHAB) catalyzed with recombinant Coprinus cinereus (rCiP) peroxidase was investigated. The kinetic measurements were performed using the spectrophotometric and fluorimetric methods. The dependences of the initial reaction rates on enzyme, substrate and hydrogen peroxide concentrations during DHAB oxidation were established, and bimolecular constants of enzyme interaction with DHAB were calculated. This research demonstrated that the initial biocatalytic oxidation rates of DHAB depend on the pH and the estimated pKa values of the active forms of rCip. This study’s findings thus contribute to a more comprehensive understanding of the biocatalytic oxidation of DHAB, providing valuable data for assessing the long-term toxicity, carcinogenesis and epigenetic effects of azo dyes in the environment. Full article
(This article belongs to the Special Issue Luminescent Dyes as Tools for Biological and Medical Applications)
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