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Oxidation in Human Health and Disease

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".

Deadline for manuscript submissions: 20 December 2024 | Viewed by 612

Special Issue Editor


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Guest Editor
Laboratori ICS de Camp de Tarragona i Terres de l'Ebre, Hospital Universitari Joan XXIII, 43007 Tarragona, Spain
Interests: cardiovascular diseases; microbiology and infectious diseases; cancer; metabolic diseases

Special Issue Information

Dear Colleagues,

There is known that oxidation plays a very important role in health and disease, being missregulation of oxidative equilibrium the underlying cause of the vast amount of diseases.

As we know, the mitochondrial are the main organ responsible of production of ROS (reactive oxygen species), but its production are closelly related to energy production.

This is the first step to understand that energy production are related to oxidative species production and the mechanisms to its control are the main tool to understand that the regulation of oxidative species are the key to maintain human health.

Not in all diseases oxidative equilibrium has been identified and measured by biochemical magnitudes. There is a large labour to get laboratory measurements done in clinical practice, reason by which has a huge value stablish relationships between oxidative species or its index and human diseases.

The aim of the present Special Issue is to collect review articles, original research, letters or short communication about oxidation in human health and human disease. We encourage the submission of manuscripts presenting reviews about the misregulation of oxidative equilibrium in human disease providing novel strategies and data to identify the relationship between misregulation of oxidative equilibrium and disease.

Dr. Isabel Fort
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • oxidative stress
  • oxidative balance
  • biochemical markers
  • reactive oxygen species
 

Published Papers (1 paper)

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Review

12 pages, 772 KiB  
Review
Redox Chemistry: Implications for Necrotizing Enterocolitis
by Grant H. Gershner and Catherine J. Hunter
Int. J. Mol. Sci. 2024, 25(15), 8416; https://doi.org/10.3390/ijms25158416 - 1 Aug 2024
Viewed by 262
Abstract
Reduction–oxidation (redox) chemistry plays a vital role in human homeostasis. These reactions play critical roles in energy generation, as part of innate immunity, and in the generation of secondary messengers with various functions such as cell cycle progression or the release of neurotransmitters. [...] Read more.
Reduction–oxidation (redox) chemistry plays a vital role in human homeostasis. These reactions play critical roles in energy generation, as part of innate immunity, and in the generation of secondary messengers with various functions such as cell cycle progression or the release of neurotransmitters. Despite this cornerstone role, if left unchecked, the body can overproduce reactive oxygen species (ROS) or reactive nitrogen species (RNS). When these overwhelm endogenous antioxidant systems, oxidative stress (OS) occurs. In neonates, OS has been associated with retinopathy of prematurity (ROP), leukomalacia, and bronchopulmonary dysplasia (BPD). Given its broad spectrum of effects, research has started to examine whether OS plays a role in necrotizing enterocolitis (NEC). In this paper, we will discuss the basics of redox chemistry and how the human body keeps these in check. We will then discuss what happens when these go awry, focusing mostly on NEC in neonates. Full article
(This article belongs to the Special Issue Oxidation in Human Health and Disease)
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Planned Papers

The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.

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