Ferroptosis: Emerging Mechanisms, Physiological Functions, and Therapeutic Applications
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".
Deadline for manuscript submissions: 20 January 2025 | Viewed by 1663
Special Issue Editor
Interests: bioinformatics; machine learning; computational biology; genomics; cancer research; single cell analysis; multi-omics analysis; spatial transcriptomics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Ferroptosis is a form of programmed cell death that is triggered by the accumulation of intracellular lipid peroxidation and is dependent on iron. Recent studies have shown that ferroptosis plays a crucial role in regulating cell oxidative stress, metabolism, and immune response, and is involved in various physiological and pathological processes in the body. It is now understood that ferroptosis can inhibit tumor growth and enhance the effectiveness of chemotherapy and immunotherapy in treating cancer. However, ferroptosis can also lead to damage in normal tissues and organs, contributing to the development of diseases such as cardiovascular and neurodegenerative disorders. By targeting ferroptosis and understanding its role in disease progression, researchers can develop new strategies for treatment and potentially improve human health outcomes.
In this Special Issue, we invite submissions of perspective, original article, review, commentary, or letter type of manuscripts that delve into topics such as, but not limited to, the following:
- ferroptosis and disease occurrence and/or development;
- ferroptosis biomarkers for lipid and/or iron metabolism in the onset and progression of diseases;
- Gene regulation of ferroptosis in diseases;
- Development and application of ferroptosis inhibitors and agonists (including nanomaterials);
- Application of ferroptosis in precision medicine and clinical transformation.
Dr. Shibiao Wan
Guest Editor
Manuscript Submission Information
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Keywords
- ferroptosis
- biomarker
- iron metabolism
- diseases
- precision medicine
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