Emerging Molecular Views in Neuroendocrinology
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 20 October 2024 | Viewed by 1117
Special Issue Editor
Special Issue Information
Dear Colleagues,
The father of neuroendocrinology was Geoffrey Wingfield Harris, who was born on June 4, 1913, in London. Prior to Harris’s activities, Marshall had shown that the central nervous system plays a role in triggering ovulation. After this observation, Harris was the first to suggest that oxytocin plays a role in the initiation of labor. Later W. Bargmann and E. Scharrer proposed the magnocellular supraoptico–paraventriculo–neurohypophyseal system. Hypophyseal portal vessels were first characterized by D. Green and G. W. Harris. Harris also made the critical observation that blood flows from the hypothalamus to the anterior pituitary. This allows the delivery of substances produced by the brain, such as neuropeptides, neurotransmitters, growth factors, and interleukins, to the hormone-producing anterior pituitary cells. The recognition of peripheral hormone feedback to the hypothalamus (long-loop feedback) and pituitary hormone feedback to the hypothalamus (short-loop feedback) was another important development in neuroendocrine research. Further progress was made with the introduction of radioimmunoassay, immunohistochemistry and in situ hybridization, as well as many other important molecular biological methods, including diagnostic and therapeutic nuclear medicine methods for the diagnosis and therapy of neuroendocrine tumors (theranostics).
This Special Issue aims to review the current literature (including original and review papers) to advance our knowledge of basic and clinical neuroendocrine researchers.
Dr. Katalin Köves
Guest Editor
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Keywords
- neuropeptides
- neurotransmitters
- neural control of ovulation
- molecular basis of neuroendocrine diseases
- theranostics
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