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Molecular Research in Spinal Cord Injury

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".

Deadline for manuscript submissions: 31 December 2024 | Viewed by 377

Special Issue Editor


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Guest Editor
Department of Neurosurgery, CHA University School of Medicine, CHA Bundang Medical Center, Seongnam-si 13496, Republic of Korea
Interests: spinal diseases (spinal cord injury, intervertebral disc degeneration, osteoporosis, etc.); pain; regeneration; stem cell; neuroprotection
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We are pleased to announce a Special Issue on “Molecular Research in Spinal Cord Injury” in the International Journal of Molecular Sciences (IJMS). This Special Issue aims to highlight cutting-edge research and advancements in the molecular mechanisms underlying spinal cord injuries (SCIs).

The scope of this Special Issue will cover a wide range of topics, including but not limited to, the following:

  • Molecular and cellular responses to spinal cord injury;
  • Stem cell therapy and regenerative medicine;
  • Tissue engineering approaches for spinal cord repair;
  • Neuroinflammation and neuroprotection;
  • Genetic and epigenetic regulation in SCIs;
  • Innovative therapeutic strategies.

This Special Issue seeks to gather contributions from leading researchers and practitioners in the field. By sharing new insights and developments, we hope to foster a deeper understanding and facilitate advancements in the treatment and management of spinal cord injuries.

Prof. Dr. Inbo Han
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • spinal cord injury
  • molecular mechanisms
  • stem cell therapy
  • tissue engineering
  • neuroinflammation
  • neuroprotection
  • genetic regulation
  • epigenetics
  • therapeutic strategies

Published Papers (1 paper)

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Review

14 pages, 1134 KiB  
Review
Therapeutic Transplantation of Human Central Nervous System Organoids for Neural Reconstruction
by Sung Jun Hong, Minsung Bock, Songzi Zhang, Seong Bae An and Inbo Han
Int. J. Mol. Sci. 2024, 25(15), 8540; https://doi.org/10.3390/ijms25158540 - 5 Aug 2024
Viewed by 271
Abstract
Damage to the central nervous system (CNS) often leads to irreversible neurological deficits, and there are currently few effective treatments available. However, recent advancements in regenerative medicine have identified CNS organoids as promising therapeutic options for addressing CNS injuries. These organoids, composed of [...] Read more.
Damage to the central nervous system (CNS) often leads to irreversible neurological deficits, and there are currently few effective treatments available. However, recent advancements in regenerative medicine have identified CNS organoids as promising therapeutic options for addressing CNS injuries. These organoids, composed of various neurons and supporting cells, have shown potential for direct repair at injury sites. CNS organoids resemble the structure and function of actual brain tissue, which allows them to adapt and function well within the physiological environment when transplanted into injury sites. Research findings suggest that CNS organoids can replace damaged neurons, form new neural connections, and promote neural recovery. This review highlights the emerging benefits, evaluates preclinical transplantation outcomes, and explores future strategies for optimizing neuroregeneration using CNS organoids. With continued research and technological advancements, these organoids could provide new hope for patients suffering from neurological deficits. Full article
(This article belongs to the Special Issue Molecular Research in Spinal Cord Injury)
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