Disease Modifying Translational Research for Neurological Disorders and Brain Damages
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: closed (31 December 2022) | Viewed by 9044
Special Issue Editors
Interests: Parkinson’s disease; Animal model; High throughput screening; Diagnostic biomarkers; Neuroinflammation
Special Issues, Collections and Topics in MDPI journals
Interests: Neuro-iflammation; Neurodegenrative disease; Stem cell application for brain: Relationship CNS and peripheral organ inflammation; Brain cancer
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Age-related neurodegenerative brain disorders and acute brain injuries are great medical challenges with no effective disease-modifying therapies. Currently available therapies are mainly centered on mitigating clinical symptoms. However, these symptomatic treatments have failed to control fundamental aspects of many brain diseases. Neurological disorders oftentimes involve not only pathological alterations within the affected neurons themselves but also unfavorable surrounding environments, thereby suggesting diverse therapeutic targets. Moreover, advanced biotechnologies have enabled us to come up with more revealing cellular and animal model systems with great flexibility in translational research.
In this regard, the aim of this Special Issue is to provide diverse translational approaches (as the format of original research articles or reviews) targeting brain-disease-associated pathological cells and molecular pathways by employing cellular and animal models of brain disorders. This Special Issue also welcomes translational and basic research on cell and animal model development which can be effectively used for high-throughput screening or preclinical studies.
Prof. Dr. Yunjong Lee
Prof. Dr. Seung Pil Yun
Guest Editors
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Keywords
- Neurodegenerative disease
- Stroke and ischemia
- Disease modeling
- Neuroinflammation
- Disease-modifying therapy
- Small molecules
- Natural compounds
- Biologics
- Preclinical study
- High-throughput screen
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