Oxidative Stress and Inflammation in Chronic Diseases: What Can Nutrition Do?

Dear Colleagues,

We are pleased to announce that we are organizing a new Special Issue whose goal is to compile evidence on how nutrition strategies can regulate oxidative stress and inflammation. Oxidative stress is viewed as an imbalance between the production of reactive oxygen species (ROS) in cells and tissue and the ability of a biological system to detoxify these reactive products. Uncontrolled oxidative stress can oxidize biomolecules or structurally modify proteins and genes to trigger signaling cascades that can lead to the onset and progression of inflammatory diseases.

Oxidative stress, inflammation and health or disease status are inter-related with each other and with nutrition. Dietary constituents with remarkably high antioxidant and anti-inflammatory capacity include many plant-derived antioxidant compounds, phytochemicals such as carotenoids, polyphenols and many others. Several of these constituents can interact with transcription factors related to anti-inflammatory and antioxidant effects. This Special Issue aims to explore antioxidants/foods containing polyphenolic antioxidants capable of interfering with the molecular signaling pathways activated by oxidative stress, as well as their possible roles in chronic inflammation-mediated disorders.

We invite authors to submit review articles and original research describing the possible nutritional approaches/bioactive natural molecules and innovative interventions in the management of oxidative stress and inflammation in chronic diseases.

We welcome original research articles and review articles.

Dr. Sara Franceschelli
Prof. Dr. Lorenza Speranza
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.