Precision Medicine and New Trends of Molecular Sciences in Vascular Disease

Dear Colleagues,

Vascular disease (VD) is the leading cause of morbidity and mortality worldwide. VD encompasses the consequences of localized atherosclerosis such as peripheral artery disease (PAD) and carotid artery stenosis (CAS); aneurysmal degeneration such as aortic aneurysm (AA); vein diseases such as chronic venous disease (CVD) and venous thromboembolism (VTE); and vascular wounds such as diabetic foot ulcer (DFU), venous leg ulcer (VLU), and arterial leg ulcer (ALU). Several risk factors contribute to the onset of subclinical disease that may progress to overt disease. Primary prevention, secondary prevention, and tertiary prevention strategies for VD are public health priorities.

In the context of precision medicine (PM), novel biomarkers related to molecular sciences research and application may be used as screening and risk-assessment tools to identify patients who are vulnerable to VD. In fact, the recent experimental technical progress related to biology, chemistry, and molecular medicine has allowed scientists to find effective biomarkers to assess and identify high-risk individuals, to ensure prompt and accurate diagnosis, and to follow up on patients that have undergone medical treatment and/or vascular and endovascular surgery procedures.

Currently, the complex approach to illness considers biology and medicine connected to social and molecular determinants of health that are strictly related to molecular sciences and biomarkers.

For this Special Issue, we invite investigators to contribute with original research and review papers that provide new insights into the underlying mechanisms of VD as well as work on new diagnostic and prognostic tools/biomarkers related to therapeutic strategies (data on molecular mechanisms or pathophysiology are essential, and papers that only contain clinical trials/data are not acceptable).

The Guest Editor Prof. Dr. Raffaele Serra and co-Guest Editors Prof. Dr. Umberto Marcello Bracale and Prof. Dr. Michele Andreucci are supported for this Special Issue by Dr. Davide Costa, University of Catanzaro and Dr. Nicola Ielapi, Sapienza University of Rome.

Prof. Dr. Raffaele Serra
Prof. Dr. Umberto Marcello Bracale
Prof. Dr. Michele Andreucci
Guest Editors

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