Neuroproteomics: Focus on Nervous System Function and Disease
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 20 January 2025 | Viewed by 347
Special Issue Editor
Interests: proteomics; synapse; dopaminergic system; neurotransmitter transporters; neuroimmune crosstalk; neurodegenerative disorders; protein–protein interactions
Special Issue Information
Dear Colleagues,
Given its outstanding heterogeneity and complexity, deciphering the cellular- and network-level mechanisms of the nervous system has been challenging, which is reflected by severe hurdles in developing efficacious pharmacological compounds without manifesting prohibiting off-target effects. Due to the major impact of neuroproteomics in shaping our understanding of the biology of the nervous system, in this Special Issue, we encourage researchers to present their latest studies focusing on the nervous system utilizing proteomics tools either conducted in vivo or in cell culture experiments. Despite constant methodological developments, significant limitations still exist in neuroproteomics that might hinder unmasking protein-level data in sufficient detail. Consequently, technical developments/refinements in sample preparation, protein identification/quantification, and bioinformatics to improve neuroproteomics data collection are within the scope of this Special Issue. Beyond original research articles, reviews and opinions, providing summaries, newly formulated hypotheses and raising current challenges within neuroproteomics are also welcome.
Dr. Balázs András Györffy
Guest Editor
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Keywords
- proteomics
- neuronal communication
- pathomechanism of nervous system disorders
- synapse
- mass spectrometry
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