Proteolysis and Proteolytic Enzymes
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".
Deadline for manuscript submissions: closed (29 February 2024) | Viewed by 1837
Special Issue Editor
Special Issue Information
Dear Colleagues,
Proteolysis is a fundamental regulatory mechanism critical for all living systems. The significance of proteolysis seems evident, and studies on proteolytic enzymes have a long and rich history. Yet, our knowledge about the function of proteases in cells and organisms is limited. It is no exaggeration to say that the biological function even of characterized proteolytic enzymes remains largely unclear. At the same time, the available data suggest that proteolysis and its dysregulation are significant factors in many pathologies. Accordingly, studies of proteolytic enzymes, proteolysis regulation, and proteolysis as regulatory factors are vital to understanding the mechanisms of pathogenesis and finding new therapeutic strategies.
The goal of this Special Issue is to present new data on proteases and discuss a broad range of their functional aspects including the proteolytic regulation, regulation of proteolysis, protease involvement in physiological and pathological processes, structural and functional relationships in their molecules, and functions of protease inhibitors. Both original studies and reviews by experts in the field are welcomed.
Dr. Ilya V. Demidyuk
Guest Editor
This special issue is assisted by Topical Advisory Panel Member Dr. Alexey Komissarov (Institute of Molecular Genetics of National Research Center "Kurchatov Institute").
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Keywords
- proteolysis
- protease
- protease inhibitor
- proteolytic regulation
- regulation of proteolysis
- proteolytic processing
- protein degradation
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