Editorial Board Members’ Collection Series: “Molecular Research in Brain Injury”
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 20 December 2024 | Viewed by 1268
Special Issue Editors
Interests: mitochondrial dysfunction; traumatic brain injury, oxidative/nitrosative stress; energy metabolism; neurodegenerations
Special Issues, Collections and Topics in MDPI journals
Interests: pharmacology; neurotherapeutics; brain ischemia; glaucoma; pain; herbal medicines
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Brain injury involves a vast number of acute and chronic pathologies triggering neurodegenerative processes to the nervous tissue, most of the time with permanent alterations of neurocognitive and/or motor functions. At the molecular level, independent on the origin of the injury, there are some common features among acute and chronic neurodegenerations. Protein misfolding/unfolding, ROS and RNS overproduction, neuroinflammation, mitochondrial dysfunction, endoplasmic reticulum stress, energy imbalance, altered cell signaling, changes in protein and gene expressions can be found in any type of brain injury. Understanding the connections and the mechanisms producing these pathological changes will help to find potential new targets for future drugs actively counteracting these processes and favoring rescue of correct nervous cell functions.
The aim of this special issue is to contribute to a better comprehension of of the aforementioned phenomena in any type of brain injury. Original and review articles are welcome. Clinical studies must contain insights into the molecular mechanisms involved in the pathology considered. Studies reporting treatments in a specific type of brain injury should contain mechanistic information of the drug action.
Prof. Dr. Giuseppe Lazzarino
Prof. Dr. Giacinto Bagetta
Guest Editors
Manuscript Submission Information
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Keywords
- brain injury
- protein misfolding
- protein unfolding
- oxidative/nitrosative stress
- energy metabolism
- mitochondrial dysfunction
- endoplasmic reticulum stress
- gene and protein expressions
- cell signaling
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