Advances in the Pathogenesis and Treatment of Hypertension
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (31 July 2023) | Viewed by 26751
Special Issue Editor
Interests: kindney; internal medicine; nephrology; dialysis; acute kidney injury; hypertension; renal tubular acidosis; hemodialysis; clinical nephrology; regulation of gene expression; renal physiology; cirrhosis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The prevalence of hypertension has escalated significantly in adults aged 30–79 years rising from 650 million to 1.28 billion over the last three decades, based on recent publications. This is especially alarming due to the “silent” nature of hypertension. Hypertension is a leading cause of premature morbidity and mortality due to stroke, cardiovascular ailment and kidney failure. If untreated, hypertension not only predisposes to stroke, but also exacerbates the outcome after ischemic or hemorrhagic stroke. In addition, hypertension can precipitate congestive heart failure. Further, hypertension can cause kidney damage and lead to kidney failure.
Major environmental risk factors for the development of hypertension include increased sodium intake, obesity, oxidative stress, physical inactivity, alcohol consumption, sleep apnea and an unhealthy diet. In addition, a number of genetic factors critical to the development of hypertension has been identified. How these genetic and environmental risk factors interact and contribute to the development of hypertension has been the subject of intensive investigation.
This issue of the International Journal of Molecular Science is bringing leading investigators in the field of hypertension and nephrology together along with the latest reviews on advances in the understanding of the role of the genetic and environmental factors responsible for the pathogenesis and treatment of hypertension.
Prof. Dr. Manoocher Soleimani
Guest Editor
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Keywords
- primary hypertension
- secondary hypertension
- gestational hypertension
- renin angiotensin aldosterone system
- metabolic syndrome
- salt overload
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