Intercellular Communication in Health and Disease
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (30 June 2019) | Viewed by 13219
Special Issue Editor
Interests: Intercellular communication; Cancer; Ephrins; Connexins; Apoptosis; Autophagy; Intracellular trafficking; Receptor tyrosine kinases
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cell–cell communication is at the core of tissue homeostasis during organism development. It is a central determinant of virtually every biological function. Cells not only exchange signaling molecules, they also engage in a corps-a-corps direct contact between their respective cytoplasmic membranes via large numbers of molecules and structural devices. Whether temporarily, as part of a developmental process, or more stably within established and less-remodeling-prone tissues, the need for cells to not only “hear” from far away cells, but also to “touch and feel” their immediate neighbors, is a vital one.
In this Special Issue, we will focus on direct cell–cell communications, involving membrane-based interactions between cells, whether via various types of junctions (gap, tight, adherens, etc.), exosomes and other vesicular structures, tunneling nanotubes, or proteins such as Ephrins, Semaphorins, etc. which function principally through membrane-to-membrane contacts.
With this general description in mind, I am pleased to invite manuscripts related to intercellular communication in either normal processes and functions or pathological conditions. Therapeutic approaches targeting these mechanisms are also within the scope of this issue.
Dr. Mustapha Kandouz
Guest Editor
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Keywords
- cell–cell communication
- gap junctions
- tight junctions
- adherens junctions
- desmosomes
- exosomes
- extracellular vesicles
- tunneling nanotubes
- intercellular bridges
- ephrins
- connexins
- pannexins
- cadherins
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