Targeting MAPK in Cancer 3.0

Dear Colleagues,

This Special Issue is a continuation of our previous Special Issue “Targeting MAPK in Cancer”.

Mitogen-activated protein kinase (MAPK) pathways are prominently involved in the onset and progression of cancer. Aberrant activation of MAPK pathways mostly affects Ras and B-Raf in the extracellular signal-regulated kinase 1/2 pathway. On the other hand, the relevance of Jun N-terminal kinase and p38 in cancer is less known, although these pathways seem to predominantly counteract, rather that to support, the malignant phenotype. Interestingly, ERK5 is emerging as an additional possible target for cancer therapy, while the possibility to exploit ERK7/ERK8-targeted therapy still lacks a rationale. In this Special Issue, we aim to highlight the contribution of all MAPK in cancer biology and to outline how to target these pathways in order to effectively reduce cancer growth and spreading.

As Guest Editor of the International Journal of Molecular Sciences (https://www.mdpi.com/journal/ijms), I am pleased to announce the opening for submission to a Special Issue entitled “Targeting MAPK in Cancer”. This Special Issue is open to both original research articles and review articles.

I look forward to your response regarding your contribution to this Special Issue.

Dr. Elisabetta Rovida
Dr. Ignazia Tusa
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.