Molecular Connection and Influence of Extracellular Matrix with Cancer
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: closed (31 October 2021) | Viewed by 52693
Special Issue Editor
Special Issue Information
Dear Colleagues,
The extracellular matrix (ECM) provides a structural basis for regulating cell functions in normal cells. However, certain ECM components are significantly altered to promote tumor progression and metastatic spread in cancer. Therefore, cancer cells need to recognize the change in the ECM and properly regulate the ECM components to support relevant cell functions. This Special Issue explores the molecular association of various ECM molecules, including structural proteins and bioactive proteins, with cancer cells via the cell surface receptor and intracellular signaling proteins of cancer cells, to understand underlying regulatory mechanisms of cancer progression and to develop new strategies to control cancer.
Prof. Dr. Eok-Soo Oh
Guest Editor
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Keywords
- extracellular matrix
- signal transduction
- adhesion receptor
- ECM remodeling
- metastasis
- tumor microenvironment
- anti-cancer strategy