Recent Advances on Meningiomas
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: closed (20 August 2023) | Viewed by 1330
Special Issue Editor
Special Issue Information
Dear Colleagues,
It is becoming increasingly apparent that complex histological and biomolecular mechanisms play a role in the genesis and recurrence of intracranial meningiomas. Major advances have been made since the description of their recurrence rate in the late 50s by Simpson—when the implementation of the surgical microscope and the advent of accurate and dedicated imaging modalities were not sufficiently powerful to bring new surgical classifications and improve prognostication pertaining to tumor recurrence and histological transformation.
Whenever a high extent of resection is achieved in low grade meningiomas, it is clear that recurrence rates are reduced. The problem is more complex with intermediate-to-high grade lesions, where recurrence is the result of a complex process involving tumor biology and location, surgical extent of resection and the patient characteristics. The implementation of next-generation diagnostic tools, such as the analysis of the methylome, is certainly promising but has not yet achieved worldwide application. Here, we invite you to submit original and review articles on the topic, focusing on the biomolecular aspects of meningiomas when it comes to their diagnosis, treatment and prognosis.
Dr. Marco V. Corniola
Guest Editor
Manuscript Submission Information
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Keywords
- intracranial meningiomas
- methylome
- biomolecular research
- microsurgery
