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Clinical Management of Patients with Heart Failure: 3rd Edition

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiovascular Medicine".

Deadline for manuscript submissions: 10 April 2026 | Viewed by 263

Special Issue Editor


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Guest Editor
1. Department VII, Internal Medicine II, Discipline of Cardiology, University of Medicine and Pharmacy “Victor Babes” Timisoara, 300041 Timisoara, Romania
2. County Emergency Hospital “Pius Brinzeu” Timisoara, Department of Cardiology, 300723 Timisoara, Romania
Interests: heart failure; systemic hypertension; acute and chronic coronary syndrome; arrhythmias; management of patients with cardiovascular diseases; cardiovascular risk factors
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Special Issue Information

Dear Colleagues,

With your continuous support and high interest in the Special Issues “Clinical Management of Patients with Heart Failure” (https://www.mdpi.com/journal/jcm/special_issues/91TCP5E3S2) and “Clinical Management of Patients with Heart Failure—2nd Edition” (https://www.mdpi.com/journal/jcm/special_issues/UT0V9ZEL70), we managed to open the third edition. The first edition closed with 16 published articles. The second edition amassed over 10 published articles in 9 months, and we closed it without extending the deadline. Both previous editions were published as reprints. We intend to continue our effort in publishing high-quality original articles, reviews, and meta-analyses, and we hope that, with your support, the third edition will be as successful as the previous ones.

Worldwide, one of the leading causes for increased morbidity and mortality is heart failure, leading to increased costs for the healthcare systems. It evolves with repeated episodes of decompensation, representing one of the most frequent reasons for hospitalization in the cardiology or internal medicine units, but also aggravating the course of other pathologies. Even in its more stable form, chronic heart failure may affect patients' well-being and quality of life, impacting their level of activity, reducing their possibility of self-care, and also generating socio-economic consequences for the diseased persons and their families.

Over the past decade, new therapeutic methods have been developed, and the availability of specialized medical care for the general population has increased, leading to better management of patients with heart failure and to an increase in the life expectancy of these subjects. Although a variety of new treatment options are available, starting with innovative drugs and continuing with invasive procedures, not to forget the lifestyle change measures, selecting the most appropriate management of heart failure is difficult, raising challenges for the medical personnel and healthcare systems while often leading to suboptimal results for the patient.

Dr. Cristina Tudoran
Guest Editor

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Keywords

  • acute heart failure
  • chronic heart failure
  • treatment options
  • management of heart failure
  • lifestyle changes
  • diagnosis of heart failure

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Published Papers (1 paper)

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Research

12 pages, 2439 KB  
Article
Added Value of MAPSE to Assess LV Systolic Function in Conventional Cardiac Pacing
by Liviu Cirin, Constantin Tudor Luca, Cristina Văcărescu, Adelina Andreea Faur-Grigori, Vlad Sabin Ivan, Ciprian Dima, Roxana Buzas, Daniel-Florin Lighezan, Simina Crișan and Dragos Cozma
J. Clin. Med. 2025, 14(19), 6880; https://doi.org/10.3390/jcm14196880 - 28 Sep 2025
Abstract
Background: Mitral annular plane systolic excursion (MAPSE) is a simple and widely used M-mode echocardiographic marker of left-ventricular longitudinal function that correlates well with left ventricular ejection fraction (LVEF). Conventional chronic right ventricle (RV) pacing is associated with left ventricle (LV) dysfunction, inducing [...] Read more.
Background: Mitral annular plane systolic excursion (MAPSE) is a simple and widely used M-mode echocardiographic marker of left-ventricular longitudinal function that correlates well with left ventricular ejection fraction (LVEF). Conventional chronic right ventricle (RV) pacing is associated with left ventricle (LV) dysfunction, inducing heart failure (HF) and leading to the development of pacing-induced cardiomyopathy (PiCM). The aim of this study is to ascertain the clinical usefulness of MAPSE in the assessment of LV function in patients with permanent RV pacing. Methods: We performed a cross-sectional association analysis, enrolling consecutive patients with pacemakers and chronic RV pacing burdens over 20% (Vp > 20%) from 2021 to 2024. All patients were assessed by standard transthoracic echocardiography (TTE) with LVEF and MAPSE among other parameters being assessed. We performed a correlation test using linear regression and plotted an ROC curve. Results: 409 patients (mean age = 68.7 year) were included, 225 men (55%) and 245 (59.9%) with dual-chamber pacemakers. The mean follow-up period was 18 ± 2 months, with HF incidence in the study group being 23.2%. The results showed that average, septal, and lateral MAPSE all correlate well with LVEF, but septal values seemed to provide the strongest correlation (r = 0.90, p < 0.001), and that a septal MAPSE cut off value of <10 mm (sensitivity 99.4, specificity 42.1, AUC = 0.89) was associated with impaired LVEF (<50%). Conclusions: MAPSE seems to corelate well with LVEF across the spectrum of HF in pts with chronic RV conventional pacing. Septal MAPSE shows the strongest correlation with LVEF, and a value of <10 mm is a cut-off for altered LVEF, making it a potentially useful marker of cardiac function in these pts. Full article
(This article belongs to the Special Issue Clinical Management of Patients with Heart Failure: 3rd Edition)
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