Autoimmune-Induced Alopecia and Emerging Therapies in Hair Loss

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Dermatology".

Deadline for manuscript submissions: 31 January 2025 | Viewed by 585

Special Issue Editor


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Guest Editor
Department of Dermatology, Universidad de Alcalá, Madrid, Spain
Interests: autoimmune-induced alopecia; clinical dermatology; hair loss

Special Issue Information

Dear Colleagues,

Autoimmune-induced alopecia, such as alopecia areata and cicatricial alopecia, occurs when the immune system mistakenly attacks hair follicles, leading to hair loss. Recent advances in treatment have focused on emerging therapies that aim to modulate immune responses and promote follicular regeneration and hair growth, spanning from medical therapies to surgical options.

The aim of this Special Issue is to review the pathophysiological mechanisms behind hair loss and to evaluate the efficacy and safety of emerging therapies in the management of this condition. It seeks to provide a comprehensive scope that includes patient management strategies and future directions in research and therapy.

Autoimmune-induced alopecia primarily includes alopecia areata, which itself can manifest in several forms such as patchy alopecia areata, where hair falls out in small patches, and alopecia totalis and universalis, where complete loss of hair occurs on the scalp or all over the body, respectively. Another type, scarring alopecia, involves the destruction of hair follicles and replacement with scar tissue, permanently impacting hair growth. Novel hair treatments have revolutionized patient management in dermatology by providing truly effective therapies. These advancements have not only improved clinical outcomes, with higher rates of hair regrowth, but have also enhanced the quality of life for patients by offering treatments with fewer side effects and better disease control.

This Special Issue spotlights novel insights into immunological underpinnings and genetic predispositions of autoimmune-induced alopecia. It also explores emerging therapies in hair loss, including new pharmacological interventions, gene therapy techniques and biotechnological advances, aiming to revolutionize treatment paradigms and patient outcomes in hair loss management.

We encourage the submission of papers focused on autoimmune-induced alopecia and new therapeutic options for any type of hair loss, including medical therapies and surgical approaches.

Dr. David Saceda-Corralo
Guest Editor

Manuscript Submission Information

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Keywords

  • autoimmune-induced alopecia
  • alopecia areata
  • cicatricial alopecia
  • occurs
  • hair loss

Published Papers (1 paper)

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Review

18 pages, 2175 KiB  
Review
Physical Treatments and Therapies for Androgenetic Alopecia
by Siddhi Bianca Camila Lama, Luis Alfonso Pérez-González, Mehmet A. Kosoglu, Robert Dennis and Daniel Ortega-Quijano
J. Clin. Med. 2024, 13(15), 4534; https://doi.org/10.3390/jcm13154534 - 2 Aug 2024
Viewed by 376
Abstract
Androgenetic alopecia, the most common cause of hair loss affecting both men and women, is typically treated using pharmaceutical options, such as minoxidil and finasteride. While these medications work for many individuals, they are not suitable options for all. To date, the only [...] Read more.
Androgenetic alopecia, the most common cause of hair loss affecting both men and women, is typically treated using pharmaceutical options, such as minoxidil and finasteride. While these medications work for many individuals, they are not suitable options for all. To date, the only non-pharmaceutical option that the United States Food and Drug Administration has cleared as a treatment for androgenetic alopecia is low-level laser therapy (LLLT). Numerous clinical trials utilizing LLLT devices of various types are available. However, a myriad of other physical treatments for this form of hair loss have been reported in the literature. This review evaluated the effectiveness of microneedling, pulsed electromagnetic field (PEMF) therapy, low-level laser therapy (LLLT), fractional laser therapy, and nonablative laser therapy for the treatment of androgenetic alopecia (AGA). It also explores the potential of multimodal treatments combining these physical therapies. The majority of evidence in the literature supports LLLT as a physical therapy for androgenetic alopecia. However, other physical treatments, such as nonablative laser treatments, and multimodal approaches, such as PEMF-LLLT, seem to have the potential to be equally or more promising and merit further exploration. Full article
(This article belongs to the Special Issue Autoimmune-Induced Alopecia and Emerging Therapies in Hair Loss)
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