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Journal of Clinical Medicine, Volume 13, Issue 16

2024 August-2 - 387 articles

Cover Story: The COVID-19 pandemic has changed the way we face medical practice and prevention. The development of effective vaccines against the SARS-CoV-2 virus was a significant tool in the battle against the pandemic. However, exacerbations of immune-mediated inflammatory diseases such as psoriasis and hidradenitis suppurativa have been reported following COVID-19 vaccination, while the underlying mechanisms by which vaccination may trigger these flares remain largely unclear. Further research is warranted in larger populations to validate the association between vaccination and possible flares of immune-mediated inflammatory diseases. We strongly encourage COVID-19 vaccination to prevent the spread of COVID-19 disease with its devastating complications, healthcare professionals should be prepared to adeptly manage the intricacies of vaccinating patients with chronic inflammatory diseases. View this paper
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Articles (387)

  • Article
  • Open Access
3 Citations
2,018 Views
11 Pages

Analysis of the Effects of Epidural Anesthesia on the Nociception Level Index (NOL®) during Abdominal Surgery

  • Alexander Ziebart,
  • David-Jonas Rothgerber,
  • Sophia Woldt,
  • Katharina Mackert,
  • Julia Heiden,
  • Michael Schuster,
  • Jens Kamuf,
  • Eva-Verena Griemert and
  • Robert Ruemmler

22 August 2024

Background: The NOL® system (PMD-200™ Nociception Level Monitor; Medasense Ltd., Ramat Gan, Israel) is used for the real-time detection of physiological nociception in anesthetized patients by assessing the parameters indicative of sympathe...

  • Article
  • Open Access
4 Citations
3,302 Views
17 Pages

Automated Quality Control Solution for Radiographic Imaging of Lung Diseases

  • Christoph Kleefeld,
  • Jorge Patricio Castillo Lopez,
  • Paulo R. Costa,
  • Isabelle Fitton,
  • Ahmed Mohamed,
  • Csilla Pesznyak,
  • Ricardo Ruggeri,
  • Ioannis Tsalafoutas,
  • Ioannis Tsougos and
  • Virginia Tsapaki
  • + 3 authors

22 August 2024

Background/Objectives: Radiography is an essential and low-cost diagnostic method in pulmonary medicine that is used for the early detection and monitoring of lung diseases. An adequate and consistent image quality (IQ) is crucial to ensure accurate...

  • Article
  • Open Access
2,000 Views
14 Pages

The Role of Vitamin D Metabolism Genes and Their Genomic Background in Shaping Cyclosporine A Dosage Parameters after Kidney Transplantation

  • Katarzyna Kotowska,
  • Bartosz Wojciuk,
  • Jerzy Sieńko,
  • Anna Bogacz,
  • Iga Stukan,
  • Sylwester Drożdżal,
  • Bogusław Czerny,
  • Karol Tejchman,
  • Grzegorz Trybek and
  • Maciej Kotowski
  • + 1 author

22 August 2024

Background: Kidney transplantation is followed by immunosuppressive therapy involving calcineurin inhibitors (CNIs) such as cyclosporin A. However, long-term high CNIs doses can lead to vitamin D deficiency, and genetic variations influencing vitamin...

  • Article
  • Open Access
1 Citations
1,798 Views
10 Pages

Perioperative Use of IgM-Enriched Immunoglobulins in Liver Transplantation Recipients at High Risk for Infections: A Preliminary Study

  • Erika Roat,
  • Martina Tosi,
  • Irene Coloretti,
  • Filippo Bondi,
  • Giovanni Chierego,
  • Stefano De Julis,
  • Marta Talamonti,
  • Emanuela Biagioni,
  • Stefano Busani and
  • Massimo Girardis
  • + 6 authors

22 August 2024

Background: Infections frequently occur after orthotopic liver transplantation (OLT) and are associated with increased mortality. In 2018, we introduced perioperative administration of intravenous immunoglobulin enriched in IgM as an optional therapy...

  • Brief Report
  • Open Access
4 Citations
2,248 Views
7 Pages

Adherence to Secondary Prevention Measures after Acute Myocardial Infarction and Its Impact on Patient Outcome—A Nationwide Perspective

  • Andreas Hammer,
  • Hana Sinkovec,
  • Marko Todorovic,
  • Florian Katsch,
  • Walter Gall,
  • Georg Duftschmid,
  • Georg Heinze,
  • Alexander Niessner and
  • Patrick Sulzgruber

22 August 2024

Objectives: Secondary prevention is crucial for reducing morbidity and mortality in patients following acute myocardial infraction (MI). However, adherence to cardiac rehabilitation (CR) and pharmacotherapy remains suboptimal despite strong guideline...

  • Article
  • Open Access
7 Citations
2,634 Views
13 Pages

Interstitial Lung Disease Phenotypes and Predictive Risk Factors in Primary Sjögren’s Syndrome

  • Gaetano La Rocca,
  • Francesco Ferro,
  • Gianluca Sambataro,
  • Elena Elefante,
  • Giovanni Fulvio,
  • Inmaculada Concepción Navarro,
  • Michele Moretti,
  • Chiara Romei,
  • Marta Mosca and
  • Chiara Baldini

22 August 2024

Background/Objectives: The prevalence of Interstitial Lung Disease (ILD) and risk factors for its development in patients with primary Sjögren’s syndrome (pSS) are still debated, possibly due to the existence of heterogeneous pSS-related I...

  • Review
  • Open Access
10 Citations
5,601 Views
31 Pages

Analysis of Research Trends in Ultrasound-Guided Acupuncture and Dry-Needling: A Scoping Review

  • Hyunwook Shin,
  • Hyeonjun Woo,
  • Yunhee Han,
  • Seungkwan Choi,
  • Jungho Jo,
  • Seojae Jeon,
  • Wonbae Ha and
  • Junghan Lee

22 August 2024

Background: This study aimed to summarize the current status of research on ultrasound-guided acupuncture and dry-needling treatment and the specific treatment methods applied to patients. Methods: A scoping review was conducted, surveying three Engl...

  • Review
  • Open Access
12 Citations
5,515 Views
13 Pages

Effects of Environmental Conditions on Athlete’s Cardiovascular System

  • Andrea Segreti,
  • Mihail Celeski,
  • Emiliano Guerra,
  • Simone Pasquale Crispino,
  • Francesca Vespasiano,
  • Lorenzo Buzzelli,
  • Chiara Fossati,
  • Rocco Papalia,
  • Fabio Pigozzi and
  • Francesco Grigioni

22 August 2024

Environmental factors such as extreme temperatures, humidity, wind, pollution, altitude, and diving can significantly impact athletes’ cardiovascular systems, potentially hindering their performance, particularly in outdoor sports. The urgency...

  • Systematic Review
  • Open Access
1 Citations
2,387 Views
15 Pages

Primary Cauda Equina Lymphoma Mimicking Meningioma

  • Pierfrancesco Lapolla,
  • Vincenza Maiola,
  • Pietro Familiari,
  • Gabriella Tomei,
  • Dominella Gangemi,
  • Sara Ienzi,
  • Roberto Arcese,
  • Mauro Palmieri,
  • Michela Relucenti and
  • Placido Bruzzaniti
  • + 5 authors

22 August 2024

Background: Spinal cord lymphomas represent a minority of extranodal lymphomas and often pose diagnostic challenges by imitating primary spinal tumors or inflammatory/infective lesions. This paper presents a unique case of primary cauda equina lympho...

  • Project Report
  • Open Access
3 Citations
2,283 Views
10 Pages

Radiographic Knee Osteoarthritis Is a Risk Factor for the Development of Dementia: Locomotive Syndrome and Health Outcomes in the Aizu Cohort Study

  • Yuji Endo,
  • Hiroshi Kobayashi,
  • Kazuyuki Watanabe,
  • Koji Otani,
  • Kenichi Otoshi,
  • Hironori Numazaki,
  • Miho Sekiguchi,
  • Mari Sato,
  • Takuya Nikaido and
  • Yoshihiro Matsumoto
  • + 2 authors

22 August 2024

Objective: Osteoarthritis is linked to dementia, but no longitudinal studies have established this connection. This prospective cohort study from the Locomotive Syndrome and Health Outcome in Aizu Cohort Study (LOHAS) aimed to determine if knee osteo...

  • Article
  • Open Access
1 Citations
1,399 Views
12 Pages

Somatic Structure and Ultrasound Parameters of the Calcaneus Bone in Combat Sports Athletes in Relation to Vitamin D3 Levels

  • Janusz Brudecki,
  • Łukasz Rydzik,
  • Wojciech Wąsacz,
  • Pavel Ruzbarsky,
  • Wojciech Czarny,
  • Marlena Warowna and
  • Tadeusz Ambroży

22 August 2024

Background/Objectives: Physical activity is widely recognized for its beneficial effects on bone density during adolescence, which could lead to enhanced bone density in later life, thus acting as a health-promoting activity with long-lasting implica...

  • Article
  • Open Access
1,388 Views
9 Pages

Occult Serologically Confirmed Cases of SARS-CoV-2 Coronavirus among the General Population in the Era of the Fourth Vaccination

  • Mori Hay Levy,
  • Neta Cohen,
  • Rotem Marom,
  • Hanoch Goldshmidt,
  • David Zeltser,
  • Michal Mizrahi,
  • Yanay Simhon,
  • Ronni Gamzu,
  • Nadir Arber and
  • Esther Saiag
  • + 2 authors

22 August 2024

Background: Asymptomatic SARS-CoV-2 infection can significantly increase the spread of the COVID-19 pandemic. We aimed to investigate the epidemiological and clinical predictors of occult serologically confirmed SARS-CoV-2 cases among the general pop...

  • Article
  • Open Access
1,251 Views
8 Pages

Characteristics and Outcome of Patients with or without Previous Implantable Cardioverter Defibrillator Interventions Undergoing Ablation for Ventricular Tachycardia

  • Gianluigi Bencardino,
  • Maria Lucia Narducci,
  • Roberto Scacciavillani,
  • Francesca Augusta Gabrielli,
  • Gemma Pelargonio,
  • Massimo Massetti,
  • Filippo Crea and
  • Gaetano Antonio Lanza

22 August 2024

Background: Catheter ablation (CA) is a well-established treatment in patients with ventricular tachycardia and appropriate implantable cardioverter defibrillator (ICD) therapies. Methods: We enrolled 57 consecutive carriers of ICD undergoing CA for...

  • Article
  • Open Access
1 Citations
2,290 Views
13 Pages

Navigating Perceived Stress: Experiences of Nursing Students Completing Internships during the COVID-19 Pandemic in Spain

  • María-Ángeles Merino-Godoy,
  • Zaida Montero Aceijas,
  • María Cano Martín,
  • Francisco-Javier Gago-Valiente,
  • Alberto Vega Abengozar,
  • Juan María Pérez Padilla and
  • Emilia Teixeira da Costa

22 August 2024

Background: University students often experience psychological strains such as academic stress, particularly as they approach the transition into the workforce. This stress may have been heightened for nursing students who completed internships durin...

  • Article
  • Open Access
2 Citations
1,823 Views
11 Pages

Skin Microvascular Dysfunction in Type 2 Diabetes Mellitus Using Laser Speckle Contrast Analysis and Association with Carotid Intima-Media Thickness

  • Stamatina Lamprou,
  • Nikolaos Koletsos,
  • Ioanna Zografou,
  • Antonios Lazaridis,
  • Gesthimani Mintziori,
  • Christina Maria Trakatelli,
  • Vasilios Kotsis,
  • Eugenia Gkaliagkousi,
  • Michael Doumas and
  • Areti Triantafyllou

22 August 2024

Background: It is established that diabetes mellitus (DM) is characterized by increased cardiovascular risk associated with subclinical atherosclerosis as well as microvascular alterations. Laser speckle contrast analysis (LASCA) is an innovative, no...

  • Review
  • Open Access
3 Citations
3,919 Views
11 Pages

22 August 2024

Purpose: Facial paralysis results from congenital or acquired facial nerve damage, leading to significant cosmetic and functional deficits. Surgical resection of parotid and midface tumors can cause facial paralysis, necessitating effective treatment...

  • Article
  • Open Access
1 Citations
2,545 Views
10 Pages

22 August 2024

Objectives: Vibration exposure is a known risk factor for developing carpal tunnel syndrome (CTS), and insufficient outcomes for surgery for CTS have been reported after such exposure. We aim to investigate whether vibration exposure affects patient-...

  • Review
  • Open Access
9 Citations
5,453 Views
17 Pages

Osteoporosis and Bone Fragility in Children: Diagnostic and Treatment Strategies

  • Giuseppe Cannalire,
  • Giacomo Biasucci,
  • Lorenzo Bertolini,
  • Viviana Patianna,
  • Maddalena Petraroli,
  • Simone Pilloni,
  • Susanna Esposito and
  • Maria Elisabeth Street

22 August 2024

The incidence of osteoporosis in children is increasing because of the increased survival rate of children with chronic diseases and the increased use of bone-damaging drugs. As childhood bone fragility has several etiologies, its management requires...

  • Article
  • Open Access
1,541 Views
12 Pages

A Modified Triangular Arthroscopic Suture-Based Fixation for Tibial Eminence Fractures: Technique, Outcome and Literature Review

  • Guy Morag,
  • Gil Rachevski,
  • Oleg Dolkart,
  • Ehud Rath,
  • Jeremy Dubin,
  • Ofir Chechik,
  • Michael Drexler and
  • Ran Atzmon

22 August 2024

Objectives: Tibial eminence fractures account for 2% to 5% of all knee injuries. Low-grade fractures, such as Type I, are typically treated conservatively, whereas high-grade fractures, such as Types III and IV, usually require surgical intervention....

  • Review
  • Open Access
4 Citations
7,137 Views
15 Pages

Impact of Phlebotomy on Quality of Life in Low-Risk Polycythemia Vera

  • Nathan Visweshwar,
  • Bradley Fletcher,
  • Michael Jaglal,
  • Damian A. Laber,
  • Ankita Patel,
  • Jennifer Eatrides,
  • Geetha Rajasekharan Rathnakumar,
  • Keshav Visweswaran Iyer,
  • Irmel Ayala and
  • Arumugam Manoharan

22 August 2024

Polycythemia vera is an indolent myeloproliferative disorder that predisposes patients to venous and arterial thrombosis and can transform into myelofibrosis and acute myeloid leukemia. Consistent phlebotomy prevents life-threatening cerebrovascular...

  • Article
  • Open Access
3 Citations
2,779 Views
15 Pages

22 August 2024

Background: Acute appendicitis (AA) is a major cause of acute abdominal pain requiring surgical intervention. Approximately 20% of AA cases are diagnosed neither early nor accurately, leading to an increased risk of appendiceal perforation and postop...

  • Systematic Review
  • Open Access
4 Citations
3,390 Views
14 Pages

A Systematic Review of Ongoing Registered Research Studies on Post-Operative Atrial Fibrillation after Cardiac Surgery

  • Ivy Quan,
  • Emilie P. Belley-Côté,
  • Jessica Spence,
  • Austine Wang,
  • Karen Sidhom,
  • Michael Ke Wang,
  • David Conen,
  • Bryan Sun,
  • Aadithya Udaya Shankar and
  • William F. McIntyre
  • + 3 authors

22 August 2024

Background/Objectives: New-onset atrial fibrillation (AF) after cardiac surgery is associated with patient-important outcomes. Uncertainty persists regarding its prevention, detection, and management. This review seeks to identify, compile, and descr...

  • Article
  • Open Access
4 Citations
2,191 Views
11 Pages

Association between Atherogenic Dyslipidemia and Subclinical Myocardial Injury in the General Population

  • Nada S. Elbadawi,
  • Moaze H. Sobih,
  • Mai Z. Soliman,
  • Mohamed A. Mostafa,
  • Richard Kazibwe and
  • Elsayed Z. Soliman

22 August 2024

Background: Subclinical myocardial injury (SCMI) is associated with an increased risk of poor cardiovascular disease (CVD) outcomes. Understanding the underlying risk factors for SCMI is crucial for the prevention and management of CVD. We hypothesiz...

  • Article
  • Open Access
4 Citations
6,575 Views
11 Pages

Treatment of Lichen Planopilaris and Frontal Fibrosing Alopecia: A Retrospective, Real-Life Analysis in a Tertiary Center in Germany

  • Henner Stege,
  • Maximilian Haist,
  • Michael Schultheis,
  • Johannes Pawlowski,
  • Miriam Wittmann,
  • Stephan Grabbe and
  • Florian Butsch

22 August 2024

Background: Lichen planopilaris (LPP) is an inflammatory cicatricial alopecia characterized by an irreversible destruction of the hair follicle resulting in its permeant destruction. The clinical presentation of LPP is a progressive patchy scarring a...

  • Article
  • Open Access
4 Citations
2,689 Views
11 Pages

Self-Efficacy and Perceived Stress in Women Experiencing Preterm Birth

  • Agata Białas,
  • Anna Nowak,
  • Karolina Kamecka,
  • Paweł Rasmus,
  • Dariusz Timler,
  • Michał Marczak,
  • Remigiusz Kozłowski and
  • Anna Lipert

22 August 2024

Background: Being an unexpected, undesired and life-threatening situation, preterm birth (PTB) is a stress-, anxiety- and depression-generating factor for women delivering prematurely. The aim of this study was to assess the relationship between self...

  • Article
  • Open Access
5 Citations
3,479 Views
11 Pages

Effect of Inter-Hospital Transfer on Mortality in Patients Admitted through the Emergency Department

  • Jei-Joon Song,
  • Si-Jin Lee,
  • Ju-Hyun Song,
  • Sung-Woo Lee,
  • Su-Jin Kim and
  • Kap-Su Han

22 August 2024

Background: Despite advancements in emergency medical systems, inter-hospital transfer (IHT) remains a critical component. Several studies have analyzed the impact of IHT on patient outcomes. Some studies have reported positive effects, indicating th...

  • Review
  • Open Access
9 Citations
3,025 Views
12 Pages

A Narrative Review of the Association between Dental Abnormalities and Chemotherapy

  • Tatsuya Akitomo,
  • Yasuko Tsuge,
  • Chieko Mitsuhata and
  • Ryota Nomura

22 August 2024

Dental abnormalities are often detected in childhood and are reported to occur with high prevalence in patients who have undergone cancer treatment or chemotherapy. We performed a literature search of PubMed from 2004 to 2024 using the terms “d...

  • Article
  • Open Access
1 Citations
1,760 Views
10 Pages

P1 and N1 Characteristics in Individuals with Normal Hearing and Hearing Loss, and Cochlear Implant Users: A Pilot Study

  • Hye Yoon Seol,
  • Soojin Kang,
  • Sungkean Kim,
  • Jihoo Kim,
  • Euijin Kim,
  • Sung Hwa Hong and
  • Il Joon Moon

22 August 2024

Background: It has been reported in many previous studies that the lack of auditory input due to hearing loss (HL) can induce changes in the brain. However, most of these studies have focused on individuals with pre-lingual HL and have predominantly...

  • Article
  • Open Access
4 Citations
3,333 Views
11 Pages

21 August 2024

Background/Objectives: Target tetra detachable coils (TTDCs) aid in achieving effective framing during the coil embolization of small intracranial aneurysms by maintaining a tetrahedral conformation within the aneurysm sac. We aimed to report the ini...

  • Feature Paper
  • Review
  • Open Access
7 Citations
9,829 Views
49 Pages

Non-Obstructive Azoospermia and Intracytoplasmic Sperm Injection: Unveiling the Chances of Success and Possible Consequences for Offspring

  • Ahmad Majzoub,
  • Marina C. Viana,
  • Arnold P. P. Achermann,
  • Isadora T. Ferreira,
  • Rita J. Laursen,
  • Peter Humaidan and
  • Sandro C. Esteves

21 August 2024

Non-obstructive azoospermia (NOA) is found in up to 15% of infertile men. While several causes for NOA have been identified, the exact etiology remains unknown in many patients. Advances in assisted reproductive technology, including intracytoplasmic...

  • Article
  • Open Access
1 Citations
1,613 Views
23 Pages

Harmonizing Heartbeats: The Mosaic of Cardiac Resynchronization Therapy Responders—A Comprehensive Exploration of Diverse Criteria and Predictors

  • Elke Boxhammer,
  • Sophie Zauner,
  • Johannes Kraus,
  • Christian Dinges,
  • Christiana Schernthaner,
  • Franz Danmayr,
  • Tobias Kolbitsch,
  • Christina Granitz,
  • Lukas J. Motloch and
  • Bernhard Strohmer
  • + 3 authors

21 August 2024

Background: Heart failure (HF) remains a challenging healthcare issue necessitating innovative therapies like cardiac resynchronization–defibrillation therapy (CRT-D). However, the definition of a CRT-D response lacks uniformity, impeding effec...

  • Article
  • Open Access
4 Citations
8,390 Views
6 Pages

Comparison of Recovery Rates of Sudden Sensorineural Hearing Loss by Age Group

  • Yeo Ra Ha,
  • Dokyoung Kim,
  • Sung Soo Kim,
  • Jae Min Lee,
  • Sang Hoon Kim and
  • Seung Geun Yeo

21 August 2024

Background: While numerous studies have been conducted on sudden sensorineural hearing loss (SSNHL), research on how treatment outcomes and prognosis vary by age remains insufficient. This study aims to investigate the differences in recovery rates a...

  • Article
  • Open Access
2 Citations
3,198 Views
10 Pages

Correction of Post-Surgical Temporal Hollowing with Adipo-Dermal Grafts: A Case Series

  • Stefano Andreoli,
  • Davide Brucato,
  • Daniel Schmauss and
  • Yves Harder

21 August 2024

Background: Surgical dissection and partial detachment of the temporalis muscle during neurosurgical procedures might result in a temporal depression known as “temporal hollowing”. Reconstructive procedures to correct this condition inclu...

  • Article
  • Open Access
4 Citations
1,719 Views
13 Pages

Could Obesity Be Related to the Increasing Incidence of Warthin Tumors?

  • Michał Gontarz,
  • Jakub Bargiel,
  • Krzysztof Gąsiorowski,
  • Tomasz Marecik,
  • Paweł Szczurowski,
  • Andrei Hramyka,
  • Joanna Kuczera,
  • Agata Wieczorkiewicz and
  • Grażyna Wyszyńska-Pawelec

21 August 2024

Background: The number of patients diagnosed with Warthin tumors (WTs) has increased significantly in recent years. The association of obesity as measured by body mass index (BMI) with the incidence of WTs remains unclear. This retrospective study ai...

  • Systematic Review
  • Open Access
7 Citations
6,546 Views
19 Pages

21 August 2024

Background: Currently, the primary strategy for addressing polycystic ovarian syndrome (PCOS) involves lifestyle modifications, with a focus on weight loss. The purpose of this meta-analysis was to assess the impact of weight loss through dietary int...

  • Article
  • Open Access
7 Citations
4,020 Views
16 Pages

Eosinophilic Bronchiectasis: Prevalence, Severity, and Associated Features—A Cohort Study

  • Raffaele Campisi,
  • Santi Nolasco,
  • Manuel Mancuso,
  • Miriam Spinella,
  • Fabio Vignera,
  • Nunzio Crimi,
  • Carlo Vancheri and
  • Claudia Crimi

21 August 2024

Background: Bronchiectasis (BE) has been traditionally associated with neutrophilic inflammation, but eosinophilic bronchiectasis (EB) has recently emerged. Data about prevalence, clinical features, and disease severity are lacking. This study aimed...

  • Article
  • Open Access
3 Citations
1,662 Views
12 Pages

Associations between Late Lactate Clearance and Clinical Outcomes in Adults with Hyperlactataemia in the Setting of Diabetic Ketoacidosis

  • Aashish Kumar,
  • Christopher Anstey,
  • Ra’eesa Doola,
  • Philippa Mcllroy,
  • Stephen Whebell,
  • Kiran Shekar,
  • Antony Attokaran,
  • Prashanti Marella,
  • Kyle White and
  • Mahesh Ramanan
  • + 3 authors

21 August 2024

Objective: This study aimed to determine the associations between lactate clearance in hyperlactataemic patients with diabetic ketoacidosis (DKA) and intensive care unit (ICU), hospital length of stay (LOS), and case-fatality. Methods: A retrospectiv...

  • Review
  • Open Access
6 Citations
3,831 Views
16 Pages

Role of Mechanical Circulatory Support in Complex High-Risk and Indicated Percutaneous Coronary Intervention: Current Indications, Device Options, and Potential Complications

  • Francesca Maria Di Muro,
  • Michele Bellino,
  • Luca Esposito,
  • Tiziana Attisano,
  • Francesco Meucci,
  • Alessio Mattesini,
  • Gennaro Galasso,
  • Carmine Vecchione and
  • Carlo Di Mario

21 August 2024

Improved expertise and technological advancements have enabled the safe and effective performance of complex and high-risk-indicated percutaneous coronary intervention (CHIP) in patients previously considered inoperable or high-risk. Mechanical circu...

  • Review
  • Open Access
22 Citations
11,586 Views
20 Pages

Ultrasound Imaging in Knee Osteoarthritis: Current Role, Recent Advancements, and Future Perspectives

  • Valerio D’Agostino,
  • Angela Sorriento,
  • Andrea Cafarelli,
  • Danilo Donati,
  • Nicolas Papalexis,
  • Alessandro Russo,
  • Gina Lisignoli,
  • Leonardo Ricotti and
  • Paolo Spinnato

21 August 2024

While conventional radiography and MRI have a well-established role in the assessment of patients with knee osteoarthritis, ultrasound is considered a complementary and additional tool. Moreover, the actual usefulness of ultrasound is still a matter...

  • Article
  • Open Access
3 Citations
1,755 Views
16 Pages

21 August 2024

Background/Objectives: The health burden of metabolic dysfunction-associated fatty liver disease (MASLD) has been increasing lately. Cardiovascular disease (CVD) is the main cause of death in MASLD patients; therefore, the treatments for MASLD should...

  • Article
  • Open Access
6 Citations
5,366 Views
15 Pages

ACL Injury Etiology in Its Context: A Systems Thinking, Group Model Building Approach

  • Charis Tsarbou,
  • Nikolaos I. Liveris,
  • Sofia A. Xergia,
  • George Papageorgiou,
  • Joanna Kvist and
  • Elias Tsepis

21 August 2024

Background/Objectives: Given the complex nature of Anterior Cruciate Ligament (ACL) injury, it is important to analyze its etiology with suitable approaches in order to formulate intervention strategies for effective prevention. The present study emp...

  • Review
  • Open Access
3 Citations
2,977 Views
16 Pages

Insights into the Interplay between the Urinary Microbiome and Bladder Cancer: A Comprehensive Review

  • Rigoberto Pallares-Mendez,
  • Aldo Brassetti,
  • Alfredo Maria Bove and
  • Giuseppe Simone

21 August 2024

New insights in the urinary microbiome have led to a better understanding being built of the shifts in bacterial representations from health to disease; these hold promise as markers for diagnosis and therapeutic responses. Although several efforts h...

  • Review
  • Open Access
2 Citations
5,613 Views
11 Pages

21 August 2024

Adenomyosis is a benign gynecologic disorder that had previously not been well studied or understood. However, it is now become a more common diagnosis with long-standing implications especially for fertility. In this literature review, the pathophys...

  • Review
  • Open Access
5 Citations
4,836 Views
19 Pages

Takotsubo Syndrome and Gender Differences: Exploring Pathophysiological Mechanisms and Clinical Differences for a Personalized Approach in Patient Management

  • Simona Giubilato,
  • Giuseppina Maura Francese,
  • Maria Teresa Manes,
  • Roberta Rossini,
  • Roberta Della Bona,
  • Laura Gatto,
  • Antonio Di Monaco,
  • Filippo Zilio,
  • Nicola Gasparetto and
  • Fabrizio Oliva
  • + 11 authors

21 August 2024

Takotsubo syndrome (TTS), also known as the broken-heart syndrome, is a reversible condition typically observed in female patients presenting for acute coronary syndromes (ACS). Despite its increasing incidence, TTS often remains undiagnosed due to i...

  • Article
  • Open Access
7 Citations
1,935 Views
13 Pages

21 August 2024

Introduction: This study explores the impact of the COVID-19 pandemic on the diagnosis of basal cell carcinoma (BCC) in Lower Silesia, Poland, comparing pre-pandemic, pandemic, and post-pandemic periods. It investigates how different medical faciliti...

  • Article
  • Open Access
3 Citations
1,920 Views
9 Pages

Prevalence and Risk Factors for Antimicrobial Resistance of Mycoplasma genitalium Infections in a High-Risk Population

  • Asher Hackett,
  • Orit Yossepowitch,
  • Yael Goor,
  • Rivka Sheffer,
  • Orna Schwartz,
  • Yonatan Sheftel,
  • Yarden Weiss and
  • Yasmin Maor

21 August 2024

Background/Objectives: Mycoplasma genitalium (MG) infections and antibiotic resistance are increasing in prevalence while treatment options are limited. Limited data exist regarding MG resistance in Israel. Our aim was to study the prevalence of...

  • Review
  • Open Access
5 Citations
6,622 Views
11 Pages

Coxsackievirus Group B Infections during Pregnancy: An Updated Literature Review

  • Carolina Longo,
  • Mauricio Saito,
  • Pedro Teixeira Castro,
  • Evelyn Traina,
  • Heron Werner,
  • Julio Elito Júnior and
  • Edward Araujo Júnior

21 August 2024

Coxsackievirus group B (CVB), a member of the Picornaviridae family and enterovirus genus, poses risks during pregnancy due to its potential to cause severe fetal and neonatal infections. Transmission primarily occurs through fecal–oral routes,...

  • Review
  • Open Access
4 Citations
3,554 Views
21 Pages

Spectrum of Non-Obstructive Coronary Artery Disease and Its Relationship with Atrial Fibrillation

  • Alexandru-Florinel Oancea,
  • Paula Cristina Morariu,
  • Ana Maria Buburuz,
  • Ionela-Larisa Miftode,
  • Radu Stefan Miftode,
  • Ovidiu Mitu,
  • Alexandru Jigoranu,
  • Diana-Elena Floria,
  • Amalia Timpau and
  • Mariana Floria
  • + 9 authors

21 August 2024

This article aims to analyze the relationship between non-obstructive coronary artery disease (NOCAD) and atrial fibrillation (AF), exploring the underlying pathophysiological mechanisms and implications for clinical management. NOCAD and AF are prev...

  • Article
  • Open Access
1,696 Views
15 Pages

Real-World Comparison of Health-Related Quality of Life Associated with Use of Immune-Checkpoint Inhibitors in Oncology Patients

  • Abdulrahman Alwhaibi,
  • Miteb A. Alenazi,
  • Saad D. Alnofaie,
  • Abdullah M. Aldekhail,
  • Rakan J. Alanazi,
  • Sultan Alghadeer,
  • Abdulrhman A. Alghamdi and
  • Saleh A. Alanazi

20 August 2024

Background: Immune checkpoint inhibitors (ICIs) offer a new treatment approach for cancer, with an improvement in patient survival. However, it remains unclear whether their use impacts the quality of life of treated patients. This study aims to comp...

  • Article
  • Open Access
7 Citations
2,534 Views
11 Pages

Usage of Tranexamic Acid for Total Hip Arthroplasty: A Matched Cohort Analysis of 144,344 Patients

  • Anubhav Thapaliya,
  • Mehul M. Mittal,
  • Terrul L. Ratcliff,
  • Varatharaj Mounasamy,
  • Dane K. Wukich and
  • Senthil N. Sambandam

20 August 2024

Background: The literature is inconclusive regarding the potential complications of tranexamic acid (TXA), an antifibrinolytic drug, for total hip arthroplasty (THA). The purpose of this study is to compare complication rates and patient outcomes bet...

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J. Clin. Med. - ISSN 2077-0383