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Cardiac Arrest and Cardiogenic Shock: Resuscitation Strategy and Prognosis
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Cardiac Arrest and Cardiogenic Shock: Resuscitation Strategy and Prognosis

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiology".

Deadline for manuscript submissions: closed (10 January 2024) | Viewed by 5006

Special Issue Editor

Prof. Dr. Won Young Kim

E-Mail Website
Guest Editor
Department of Emergency Medicine, University of Ulsan College of Medicine, Asan Medical Center, 88, Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Republic of Korea
Interests: cardiac arrest; post-cardiac arrest care; sepsis; septic shock
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Despite the significant improvement of cardiogenic shock and cardiac arrest care, resuscitating these patients is still challenging. Cardiac arrest is also a complex lethal condition with a public health burden due to irreversible functional disability. Therefore, better resuscitation strategies are necessary.

Another issue of cardiogenic shock and cardiac arrest is quickly obtaining reliable information on the probability of good neurological outcome. A reliable prognostic tool would be very helpful to tailor medical therapies to the appropriate patients.

This Special Issue of the Journal of Clinical Medicine on “Cardiac Arrest and Cardiogenic Shock: Resuscitation Strategy and Prognosis” aims to collect brilliant contributions from worldwide experts in the field of resuscitation for cardiac arrest and cardiogenic shock. Invited topics include clinical management and prognosis of cardiogenic shock, resuscitation strategies, prediction of good neurologic outcome, trends in resuscitation outcomes, resuscitation modalities, and post-resuscitation care.

Prof. Dr. Won Young Kim
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cardiac arrest
  • cardiogenic shock
  • post-cardiac-arrest care
  • neurologic outcome

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Published Papers (2 papers)

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9 pages, 616 KiB  
Article
Inodilators May Improve the In-Hospital Mortality of Patients with Cardiogenic Shock Undergoing Veno-Arterial Extracorporeal Membrane Oxygenation
by Mijoo Kim, Seok-Woo Seong, Pil Sang Song, Jin-Ok Jeong, Jeong Hoon Yang, Hyeon-Cheol Gwon, Young-Guk Ko, Cheol Woong Yu, Woo Jung Chun, Woo Jin Jang, Hyun-Joong Kim, Jang-Whan Bae, Sung Uk Kwon, Hyun-Jong Lee, Wang Soo Lee, Sang-Don Park, Sung Soo Cho and Jae-Hyeong Park
J. Clin. Med. 2022, 11(17), 4958; https://doi.org/10.3390/jcm11174958 - 24 Aug 2022
Cited by 4 | Viewed by 2377
Abstract
Although inodilators (dobutamine and milrinone) are widely used empirically for cardiogenic shock (CS), the efficacy of inodilators for patients with CS undergoing veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is controversial. We evaluated the effects of inodilators on clinical outcomes using the RESCUE (REtrospective and [...] Read more.
Although inodilators (dobutamine and milrinone) are widely used empirically for cardiogenic shock (CS), the efficacy of inodilators for patients with CS undergoing veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is controversial. We evaluated the effects of inodilators on clinical outcomes using the RESCUE (REtrospective and prospective observational Study to investigate Clinical oUtcomes and Efficacy of left ventricular assist device for Korean patients with cardiogenic shock; NCT02985008) registry. We selected and analyzed the clinical outcomes of 496 patients who underwent VA-ECMO and did or did not receive inodilators. Of the 496 patients, 257 (51.8%) died during hospitalization. We selected 191 matched pairs to adjust for baseline clinical characteristics after 1:1 propensity score matching (PSM). The univariate and multivariate analyses showed that the inodilator group had significantly lower in-hospital mortality than the no-inodilator group (unadjusted hazard ratio [HR], 0.768; 95% confidence interval [CI], 0.579–1.018; p = 0.066, adjusted HR, 0.702; 95% CI, 0.552–0.944; p = 0.019). For patients with CS undergoing VA-ECMO, inodilators may improve clinical outcomes. Full article
(This article belongs to the Special Issue Cardiac Arrest and Cardiogenic Shock: Resuscitation Strategy and Prognosis)
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12 pages, 1495 KiB  
Systematic Review
Blood Pressure Targets for Out-of-Hospital Cardiac Arrest: A Systematic Review and Meta-Analysis
by Shir Lynn Lim, Christopher Jer Wei Low, Ryan Ruiyang Ling, Rehena Sultana, Victoria Yang, Marcus E. H. Ong, Yew Woon Chia, Vijay Kumar Sharma and Kollengode Ramanathan
J. Clin. Med. 2023, 12(13), 4497; https://doi.org/10.3390/jcm12134497 - 5 Jul 2023
Cited by 2 | Viewed by 2043
Abstract
Background: With ideal mean arterial pressure (MAP) targets in resuscitated out-of-hospital cardiac arrest (OHCA) patients unknown, we performed a meta-analysis of randomised controlled trials (RCTs) to compare the effects of higher versus lower MAP targets. Methods: We searched four databases until 1 May [...] Read more.
Background: With ideal mean arterial pressure (MAP) targets in resuscitated out-of-hospital cardiac arrest (OHCA) patients unknown, we performed a meta-analysis of randomised controlled trials (RCTs) to compare the effects of higher versus lower MAP targets. Methods: We searched four databases until 1 May 2023 for RCTs reporting the effects of higher MAP targets (>70 mmHg) in resuscitated OHCA patients and conducted random-effects meta-analyses. The primary outcome was mortality while secondary outcomes were neurological evaluations, arrhythmias, acute kidney injury, and durations of mechanical ventilation and ICU stay. We conducted inverse-variance weighted strata-level meta-regression against a proportion of non-survivors to assess differences between reported MAPs. We also conducted a trial sequential analysis of RCTs. Results: Four RCTs were included. Higher MAP was not associated with reduced mortality (OR: 1.09, 95%-CI: 0.84 to 1.42, p = 0.51), or improved neurological outcomes (OR: 0.99, 95%-CI: 0.77 to 1.27, p = 0.92). Such findings were consistent despite additional sensitivity analyses. Our robust variance strata-level meta-regression revealed no significant associations between mean MAP and the proportion of non-survivors (B: 0.029, 95%-CI: −0.023 to 0.081, p = 0.162), and trial sequential analysis revealed no meaningful survival benefit for higher MAPs. Conclusions: A higher MAP target was not significantly associated with improved mortality and neurological outcomes in resuscitated OHCA patients. Full article
(This article belongs to the Special Issue Cardiac Arrest and Cardiogenic Shock: Resuscitation Strategy and Prognosis)
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