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Cardiovascular and Cerebrovascular Emergencies: Advances in Clinical Research
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Cardiovascular and Cerebrovascular Emergencies: Advances in Clinical Research

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiovascular Medicine".

Deadline for manuscript submissions: 30 April 2025 | Viewed by 1256

Special Issue Editor

Dr. Andrew Fu Wah Ho

E-Mail Website
Guest Editor
1. Department of Emergency Medicine, Singapore General Hospital, Singapore 169608, Singapore
2. Pre-Hospital & Emergency Research Centre, Duke-National University of Singapore Medical School, Singapore 169857, Singapore
3. Centre for Population Health Research and Implementation, Singhealth Regional Health System, Singapore 168753, Singapore
Interests: emergency medicine; resuscitation science; environmental epidemiology; public health

Special Issue Information

Dear Colleagues,

Cardiovascular and neurovascular emergencies are some of the most catastrophic and time-sensitive diseases. However, therein lies exciting opportunities to improve clinical outcomes.

This Special Issue of the Journal of Clinical Medicine focuses the readers' attention on emerging topics on the diagnosis, risk stratification, prognostication, and treatment of cardiovascular and neurovascular emergencies. Of particular interest is the inclusion of multidisciplinary studies that involve the interaction of the heart and brain.

This Special Issue will be an invaluable resource for emergency physicians, intensivists, cardiologists, and scientists working in this space, providing cutting-edge reports ranging from early exploratory studies that stimulate further research to practical guidance for clinicians. The high-quality content, provided by internationally renowned experts from various institutions, will make this Special Issue a must-read for anyone interested in this field.

Dr. Andrew Fu Wah Ho
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cardiovascular emergencies
  • neurovascular emergencies
  • stroke
  • cardiac arrest
  • acute myocardial infarction

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Further information on MDPI's Special Issue polices can be found here.

Published Papers (2 papers)

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Research

9 pages, 228 KiB  
Article
What Is the Efficacy of Bilateral Antegrade Cerebral Perfusion in Cerebral Protection?
by Hasan Iner, Ihsan Peker, Erturk Karaagac, Serkan Yazman, Huseyin Durmaz, Cagri Kandemir, Tahsin Murat Tellioglu, Orhan Gokalp, Levent Yilik and Ali Gurbuz
J. Clin. Med. 2024, 13(23), 7452; https://doi.org/10.3390/jcm13237452 - 7 Dec 2024
Viewed by 426
Abstract
Background/Objectives: Acute type A aortic dissection is among the many types of catastrophic cardiovascular emergencies. The development of serious morbidity, especially neurological complications after the operation, remains a huge threat. We aimed to present comparatively the results of using unilateral or bilateral antegrade [...] Read more.
Background/Objectives: Acute type A aortic dissection is among the many types of catastrophic cardiovascular emergencies. The development of serious morbidity, especially neurological complications after the operation, remains a huge threat. We aimed to present comparatively the results of using unilateral or bilateral antegrade cerebral perfusion to minimize these threats and to demonstrate the postoperative effects of antegrade cerebral perfusion choices. Methods: The 147 patients who underwent emergency acute type A aortic dissection surgery between January 2018 and January 2023 were evaluated retrospectively. The patients were divided into two groups: those who underwent unilateral antegrade cerebral perfusion (Group 1) (n = 89) and those who underwent bilateral antegrade cerebral perfusion (Group 2) (n = 59). Baseline demographics, and preoperative, operative, and postoperative data of patients were compared statistically. Results: When the analyses of baseline demographics, and preoperative and operative data were evaluated, no significant difference was found between the groups. In addition, when comparing postoperative results, no statistical difference was found between the groups except for new-onset permanent neurological complications. The rate of postoperative new-onset permanent neurological complications was found to be 17.9% in group 1, where unilateral antegrade cerebral perfusion was applied, and 5.1% in group 2, where bilateral antegrade cerebral perfusion was applied, and this comparison was statistically significant. Conclusions: The competence of the Willis Polygon should not be relied upon without any evidence, and we believe that bilateral antegrade cerebral perfusion can be performed with a technique that does not compromise surgical comfort. Full article
(This article belongs to the Special Issue Cardiovascular and Cerebrovascular Emergencies: Advances in Clinical Research)
16 pages, 2161 KiB  
Article
Validation of EuroSCORE II, ACEF Score, CHA2DS2-VASc, and CHA2DS2-VA in Patients Undergoing Left Main Coronary Artery Angioplasty: Analysis from All-Comers BIA-LM Registry
by Emil Julian Dąbrowski, Paweł Kralisz, Konrad Nowak, Kamil Gugała, Przemysław Prokopczuk, Grzegorz Mężyński, Michał Święczkowski, Sławomir Dobrzycki and Marcin Kożuch
J. Clin. Med. 2024, 13(22), 6907; https://doi.org/10.3390/jcm13226907 - 16 Nov 2024
Viewed by 506
Abstract
Background: Simple surgical and clinical risk scores are useful in mortality prediction. Aims: The study’s aim was to validate three scores in real-world registry of percutaneous coronary intervention (PCI) for the left main coronary artery (LMCA). Methods: All data were [...] Read more.
Background: Simple surgical and clinical risk scores are useful in mortality prediction. Aims: The study’s aim was to validate three scores in real-world registry of percutaneous coronary intervention (PCI) for the left main coronary artery (LMCA). Methods: All data were obtained from the BIA-LM Registry. Discrimination and calibration of EuroSCORE II, ACEF, CHA2DS2-VASc, and CHA2DS2-VA were assessed with receiver operating characteristic (ROC) curves analysis and Hosmer–Lemeshow (HL) test. Results: The final cohort included 851 patients, median age was 71, and 156 patients had history of previous coronary artery bypass grafting (CABG). Median EuroSCORE II, ACEF, CHA2DS2-VASc, and CHA2DS2-VA were 3.1% (IQR 5.4%), 1.56 (IQR 0.9), 4 (IQR 2), and 4 (IQR 2), respectively. In the short- (30 days) and long-term (mean 4.1 years), there were 27 and 318 deaths. In short-term, EuroSCORE II showed the best discrimination in the overall population and subgroup with unprotected LMCA [area under the curve (AUC) 0.804, 95% CI 0.717–0.890 and AUC 0.826, 95% CI 0.737–0.913, respectively, p < 0.001 for comparisons with other models), with the best cut-off value at 7.1%. In long-term observation, EuroSCORE II and ACEF showed good predictive value (overall population: AUC 0.716, 95% CI 0.680–0.750 and AUC 0.725, 95% CI 0.690–760, respectively). In short- and long-term observation, EuroSCORE II and ACEF showed poor calibration (HL test p < 0.05) as compared to CHA2DS2-VASc (HL test p = 0.40 and 0.18). Conclusions: EuroSCORE II showed good mortality prediction in short-term observation; however, its predicted risk should be interpreted with caution due to poor calibration. ACEF and EuroSCORE II may be useful in long-term mortality prediction. Full article
(This article belongs to the Special Issue Cardiovascular and Cerebrovascular Emergencies: Advances in Clinical Research)
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