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Clinical Diagnosis and Treatments of Spinal Tumors

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Orthopedics".

Deadline for manuscript submissions: closed (28 July 2024) | Viewed by 663

Special Issue Editor


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Guest Editor
1. Department of Neurosurgery, Oakland University William Beaumont School of Medicine, Rochester Hills, MI, USA
2. Director of Spine Tumor Program, Corewell Health William Beaumont University Hospital, Royal Oak, MI, USA
3. Spine & Brain Surgery Specialists, Royal Oak, MI, USA
Interests: spine tumors; minimally invasive spine surgery; kyphoplasty and radiofrequency ablation

Special Issue Information

Dear Colleagues,

Primary and metastatic tumors of the spine and spinal cord are challenging entities. As targeted treatment for cancer continues to improve survival, more and more patients develop metastases in their spine during the course of their treatment. With advancing technologies and minimally invasive techniques, the treatment paradigms for spinal tumors are continuously evolving. Modern treatments include separation surgery, en bloc resection, minimally invasive instrumentation, stereotactic radiosurgery, laser interstitial therapy, radiofrequency ablation, kyphoplasty, and robotic surgical techniques. To optimize the treatment of our patients, we must be aware of the available treatment options. The multidisciplinary management of spinal tumors has the potential to improve outcomes, survival and quality of life.

This Special Issue welcomes advances in the clinical diagnosis and treatment of spinal tumors, including both original research articles and reviews.

Dr. Daniel K. Fahim
Guest Editor

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Keywords

  • spine tumors
  • metastatic spine tumors
  • stereotactic radiosurgery
  • minimally invasive spine surgery
  • radiofrequency ablation
  • kyphoplasty

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Published Papers (1 paper)

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Research

11 pages, 2829 KiB  
Article
En Bloc Total Vertebrectomy of the Thoracic and Lumbar Spine
by Eleonora Schneider, Marie-Christine Lutschounig, Jennifer Straub, Klemens Vertesich, Petra Krepler, Anna Rienmüller, Susanna Lang, Iris-Melanie Noebauer-Huhmann, Christoph Böhler and Reinhard Windhager
J. Clin. Med. 2024, 13(17), 5312; https://doi.org/10.3390/jcm13175312 - 8 Sep 2024
Viewed by 424
Abstract
Background/Objectives: We evaluated the outcomes of patients undergoing en bloc total vertebrectomy at our institution within the last three decades. The aim of our study was to analyse the oncological and neurological outcomes and the changes over time. Methods: We included [...] Read more.
Background/Objectives: We evaluated the outcomes of patients undergoing en bloc total vertebrectomy at our institution within the last three decades. The aim of our study was to analyse the oncological and neurological outcomes and the changes over time. Methods: We included 22 consecutive patients treated with a total vertebrectomy at our institution between January 1990 and December 2022. The standard follow-up protocol for sarcoma patients was performed. Early complications were defined as complications within the first three months postoperatively. Local recurrence was defined as the reoccurrence of a tumour at least four months after surgery. Adequate statistical methods were applied to evaluate the survival rates and the influence of potential risk factors. A p-value of <0.05 was considered statistically significant. Results: From 1990 to 2010, five total vertebrectomies were performed each decade, whereas twelve patients underwent the procedure in the period from 2010 to 2022. The mean follow-up period was 101.25 months (±112; 2–339). The one-, five- and ten-year overall survival rates were 91% (CI = (0.79; 1.00)), 59% (CI = (0.37; 0.81)) and 51% (CI = (0.27; 0.75)), respectively. For soft tissue tumours, the average overall survival was 6.2 years, whereas, for bone sarcomas, it was 13.6 years. None of the patients with wide surgical margins developed local recurrence. Complications necessitating revision procedures occurred in 54% of all cases. Conclusions: A total vertebrectomy is a highly demanding procedure, requiring accurate patient selection, meticulous preoperative planning and a highly collaborative interdisciplinary team. Adequate surgical treatment seems to be indispensable when aiming for curative treatment. Owing to the rarity of the indications, this procedure should be restricted to large tumour centres. Full article
(This article belongs to the Special Issue Clinical Diagnosis and Treatments of Spinal Tumors)
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